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Titolo:
LOW-DOSE MELATONIN IMPROVES SLEEP IN HEALTHY MIDDLE-AGED SUBJECTS
Autore:
ATTENBURROW MEJ; COWEN PJ; SHARPLEY AL;
Indirizzi:
UNIV OXFORD,LITTLEMORE HOSP,DEPT PSYCHIAT,PSYCHOPHARMACOL RES UNIT OXFORD OX4 4XN ENGLAND UNIV OXFORD,LITTLEMORE HOSP,DEPT PSYCHIAT,PSYCHOPHARMACOL RES UNIT OXFORD OX4 4XN ENGLAND
Titolo Testata:
Psychopharmacology
fascicolo: 2, volume: 126, anno: 1996,
pagine: 179 - 181
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMANS;
Keywords:
MELATONIN; SLEEP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Physical, Chemical & Earth Sciences
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
M.E.J. Attenburrow et al., "LOW-DOSE MELATONIN IMPROVES SLEEP IN HEALTHY MIDDLE-AGED SUBJECTS", Psychopharmacology, 126(2), 1996, pp. 179-181

Abstract

We studied the effects of single evening doses of melatonin (0.3 mg and 1.0 mg orally) on polysomnographically measured sleep in 15 healthymiddle-aged volunteers, using a placebo-controlled, double-blind, cross-over design. Compared to placebo, the 1.0 mg dose of melatonin significantly increased Actual Sleep Time, Sleep Efficiency, non-REM Sleepand REM Sleep Latency. These data are consistent with the hypothesis that low dose melatonin has hypnotic effects in humans. It is possiblethat administered melatonin may have a role to play in the treatment of sleep disorders.

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Documento generato il 10/07/20 alle ore 09:20:48