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Titolo:
PREGNANCY AND CERVICAL INFECTION WITH HUMAN PAPILLOMAVIRUSES
Autore:
MORRISON EAB; GAMMON MD; GOLDBERG GL; VERMUND SH; BURK RD;
Indirizzi:
630 W 168TH ST,HP 6 NEW YORK NY 10032 COLUMBIA UNIV,COLL PHYS & SURG,DEPT MED NEW YORK NY 10027 COLUMBIA UNIV,COLL PHYS & SURG,SCH PUBL HLTH NEW YORK NY 10027 ALBERT EINSTEIN COLL MED,DEPT OBSTET & GYNECOL NEW YORK NY 00000 ALBERT EINSTEIN COLL MED,DEPT EPIDEMIOL & SOCIAL MED NEW YORK NY 00000 ALBERT EINSTEIN COLL MED,DEPT PEDIAT NEW YORK NY 00000 ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL NEW YORK NY 00000
Titolo Testata:
International journal of gynaecology and obstetrics
fascicolo: 2, volume: 54, anno: 1996,
pagine: 125 - 130
SICI:
0020-7292(1996)54:2<125:PACIWH>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENITAL HUMAN PAPILLOMAVIRUS; RISK-FACTORS; DEOXYRIBONUCLEIC-ACID; PREVALENCE; WOMEN; DETERMINANTS; ASSOCIATION; NEOPLASIA; CELLS; PCR;
Keywords:
PREGNANCY; HUMAN PAPILLOMAVIRUS; PARITY; AGE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
E.A.B. Morrison et al., "PREGNANCY AND CERVICAL INFECTION WITH HUMAN PAPILLOMAVIRUSES", International journal of gynaecology and obstetrics, 54(2), 1996, pp. 125-130

Abstract

Objective: This investigation was undertaken to assess whether pregnancy represents a risk factor for human papillomavirus (HPV) infection which is independent of age and other known HPV risk factors, Methods:One hundred eighty-nine women were enrolled from the outpatient clinics of a large municipal hospital. The subjects completed a self-administered questionnaire and underwent a gynecologic examination which included a cervicovaginal lavage. Lavage samples were assessed for the presence of HPV DNA by restriction enzyme analysis and Southern blot hybridization, Statistical significance was assessed by the chi(2)-test, Logistic regression was used to assess the association between pregnancy and HPV while controlling for the effect of other risk factors. Results: The prevalence odds ratio (FOR) for the association of pregnancyand HPV infection was 2.2 (95% C.I. 1.1-4.5), The prevalence of HPV increased with increasing gestational age (HPV prevalence of 18.9% among non-pregnant women vs. 27.3% in those in the first 12 weeks of pregnancy and 39.7% in those who were past the 12th week of pregnancy). Although statistical significance was not achieved in a multivariate model which controlled for age, race/ethnicity, education, age at first coitus, number of sexual partners within the last year and parity, the FOR associated with the current pregnancy (FOR = 2.1) was not substantially changed by correcting for these risk factors, suggesting that these factors were not significant confounders of the association betweenpregnancy and HPV infection. Conclusion: Current pregnancy is associated with a modestly increased prevalence of cervical HPV infection. This association appears to be independent of age and other major HPV risk factors.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:50:23