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Titolo:
INDICATIONS FOR CLINICAL-APPLICATION OF P OSITRON EMISSION TOMOGRAPHYIN CARDIOLOGY
Autore:
SCHWAIGER M; BULL U; HOR G; HUNDESHAGEN H; MULLERGARTNER HW; KNAPP WH; MOSER E; NOTOHAMIPRODJO G; REINERS C; RESKE SN; SCHICHA H; VOMDAHL J; NIENABER C; SECHTEM U; WOLPERS G; ZIMMERMANN R;
Indirizzi:
TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,NUKL MED KLIN & POLIKLIN,ISMANINGER STR 22 D-81675 MUNICH GERMANY TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,PET ARBEITSGRP D-81675 MUNICH GERMANY TECH UNIV MUNICH,KLINIKUM RECHTS ISAR,ARBEITSKREIS NUKL KARDIOL D-81675 MUNICH GERMANY
Titolo Testata:
Zeitschrift fur Kardiologie
fascicolo: 7, volume: 85, anno: 1996,
pagine: 453 - 468
SICI:
0300-5860(1996)85:7<453:IFCOPO>2.0.ZU;2-S
Fonte:
ISI
Lingua:
GER
Soggetto:
CORONARY-ARTERY DISEASE; MYOCARDIAL BLOOD-FLOW; LEFT-VENTRICULAR DYSFUNCTION; ASSESSING VIABLE MYOCARDIUM; COMPUTED-TOMOGRAPHY; OXIDATIVE-METABOLISM; N-13 AMMONIA; NONINVASIVE QUANTIFICATION; GLUCOSE-UTILIZATION; F-18 FLUORODEOXYGLUCOSE;
Keywords:
POSITRON EMISSION TOMOGRAPHY; CORONARY ARTERY DISEASE; MYOCARDIAL PERFUSION; MYOCARDIAL VIABILITY; DIAGNOSTIC VALUE; INDICATION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
141
Recensione:
Indirizzi per estratti:
Citazione:
M. Schwaiger et al., "INDICATIONS FOR CLINICAL-APPLICATION OF P OSITRON EMISSION TOMOGRAPHYIN CARDIOLOGY", Zeitschrift fur Kardiologie, 85(7), 1996, pp. 453-468

Abstract

Positron emission tomography (PET) respresents the most advanced scintigraphic technique which allows accurate qualitative and quantitativeassessment of regional myocardial tracer distribution. Besides its well documented potential as a research tool, PET has gained increasing clinical acceptance in cardiology. At the current time, the two most important clinical indications are the detection of coronary artery disease using perfusion traces and the evaluation of patients with advanced coronary artery disease and impaired left ventricular function for identification of tissue viability using metabolic tracers. Direct comparison of PET and SPECT imaging has shown improved diagnostic accuracy of PET imaging for detection of CAD. However, the high cost and limited availability of this technique limit its widespread application asroutine method for detection of CAD. Nevertheless, for determination of the functional significance of regional stenoses, PET is the most accurate non-invasive method available. Numerous studies using PET FDG-imaging have demonstrated the high diagnostic accuracy of metabolic imaging for the detection of tissue viability. Recovery of function following revascularization can be predicted with high positive and negative predictive value. Based on its documented diagnostic performance, PET is recommended for assessment of tissue viability especially in patients with severely impaired left ventricular function who are candidates for revascularization or cardiac transplantation. Promising new advances in imaging technology may reduce the costs of PET instrumentation and, therefore, widen the clinical application of this technique.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 05:58:34