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Titolo:
AMBULATORY BLOOD-PRESSURE ON AND OFF CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY FOR THE SLEEP APNEA HYPOPNEA SYNDROME - EFFECTS IN NON-DIPPERS/
Autore:
ENGLEMAN HM; GOUGH K; MARTIN SE; KINGSHOTT RN; PADFIELD PL; DOUGLAS NJ;
Indirizzi:
ROYAL INFIRM,SCOTTISH NATL SLEEP LAB,LAURISTON PL EDINBURGH EH3 9YW MIDLOTHIAN SCOTLAND UNIV EDINBURGH,DEPT MED,RESP MED UNIT EDINBURGH EH8 9YL MIDLOTHIAN SCOTLAND UNIV EDINBURGH,WESTERN GEN HOSP,DEPT MED EDINBURGH EH4 2XU MIDLOTHIANSCOTLAND
Titolo Testata:
Sleep
fascicolo: 5, volume: 19, anno: 1996,
pagine: 378 - 381
SICI:
0161-8105(1996)19:5<378:ABOAOC>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR HYPERTROPHY; SYSTEMIC HYPERTENSION; HYPOPNEA SYNDROME; APNEA SYNDROME; PREVALENCE; MORTALITY; CPAP; MEN;
Keywords:
BLOOD PRESSURE; SLEEP APNEA SYNDROMES; CONTINUOUS POSITIVE AIRWAY PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
H.M. Engleman et al., "AMBULATORY BLOOD-PRESSURE ON AND OFF CONTINUOUS POSITIVE AIRWAY PRESSURE THERAPY FOR THE SLEEP APNEA HYPOPNEA SYNDROME - EFFECTS IN NON-DIPPERS/", Sleep, 19(5), 1996, pp. 378-381

Abstract

Ambulatory blood pressure (BP) monitoring was performed in 13 patients with the sleep apnea/hypopnea syndrome (SAHS) during a randomized, placebo-controlled crossover trial of the effects of continuous positive airway pressure (CPAP) therapy. BP was monitored at half-hourly intervals for a 24-hour period both on CPAP and on an oral placebo, each given for a minimum of 3 weeks. Objective effective CPAP use averaged 4.3 hours per night. Weight and anti-hypertensive medications remained stable over the study period. Systolic, diastolic and mean arterial BPfor 24-hour, daytime and nighttime periods were not significantly different on placebo compared to CPAP. Those patients with no significantovernight fall in BP on placebo (''non-dippers'') showed a significant improvement in daytime mean arterial BP on CPAP (98 +/- 4 mm Hg) compared to placebo (102 +/- 4 mm Hg; p = 0.01). These findings, in a well-controlled trial, suggest that BP is not reduced by CPAP in a heterogeneous group of SAHS patients, but it may be selectively improved in those patients most at risk for cardiovascular morbidity and mortality.

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Documento generato il 26/01/20 alle ore 16:13:22