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Titolo:
ADVERSE EFFECT OF PREGNANCY ON HIGH-DENSITY-LIPOPROTEIN (HDL) CHOLESTEROL IN YOUNG-ADULT WOMEN - THE CARDIA STUDY
Autore:
LEWIS CE; FUNKHOUSER E; RACZYNSKI JM; SIDNEY S; BILD DE; HOWARD BV;
Indirizzi:
UNIV ALABAMA,DIV PREVENT MED,BEHAV MED UNIT,1717 11TH AVE S,ROOM 734 BIRMINGHAM AL 35205 UNIV ALABAMA,SCH PUBL HLTH,DEPT EPIDEMIOL BIRMINGHAM AL 35294 UNIV ALABAMA,SCH PUBL HLTH,DEPT HLTH BEHAV BIRMINGHAM AL 35294 KAISER PERMANENTE,DIV RES OAKLAND CA 00000 NHLBI,DIV EPIDEMIOL & CLIN APPLICAT BETHESDA MD 20892 MEDLANT RES INST WASHINGTON DC 00000
Titolo Testata:
American journal of epidemiology
fascicolo: 3, volume: 144, anno: 1996,
pagine: 247 - 254
SICI:
0002-9262(1996)144:3<247:AEOPOH>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; DEPENDENT DIABETES-MELLITUS; REPRODUCTIVE HISTORY; DEHYDROEPIANDROSTERONE-SULFATE; POSTPARTUM LACTATION; LIPID-METABOLISM; 1ST PREGNANCY; INSULIN; PARITY; RISK;
Keywords:
LIPOPROTEINS; LIPOPROTEINS, HDL CHOLESTEROL; PARITY; REPRODUCTION; WOMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
54
Recensione:
Indirizzi per estratti:
Citazione:
C.E. Lewis et al., "ADVERSE EFFECT OF PREGNANCY ON HIGH-DENSITY-LIPOPROTEIN (HDL) CHOLESTEROL IN YOUNG-ADULT WOMEN - THE CARDIA STUDY", American journal of epidemiology, 144(3), 1996, pp. 247-254

Abstract

The authors analyzed data from the Coronary Artery Risk Development in Young Adults (CARDIA) Study in order to examine associations betweenparity and lipoproteins. Of 2,787 women recruited in 1985-1986, 2,534(91%) returned in 1987-1988 and 2,393 (86%) returned in 1990-1991 forrepeat evaluations, Two-year change (1987-1988 to 1985-1986) in high density lipoprotein (HDL) cholesterol was significantly different among the parity groups, HDL cholesterol decreased in women who had their first pregnancy of at least 28 weeks duration during follow-up (mean +/- standard error, -3.5 +/- 1.2 mg/dl), and this change was significantly different from the increase in women parous at baseline who had nofurther pregnancies (2.5 +/- 0.3 mg/dl) and in nullipara (2.4 +/- 0.3mg/dl). There was a nonsignificant trend for a greater decrease in HDL(2) cholesterol fraction in the primipara compared with the other groups. The HDL cholesterol decrease remained significant after controlling for race, age, education, oral contraceptive use, and changes in body mass index, waist-hip ratio, physical activity, smoking status, andalcohol intake. Change in HDL cholesterol was also significantly different among the parity groups in analyses of pregnancies that occurredduring the subsequent 3 years of follow-up, There were no differencesfor change in LDL cholesterol or triglycerides. Potential mechanisms for a detrimental effect of pregnancy on HDL cholesterol include hormonal, body composition, or life-style/behavioral changes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 14:43:57