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Titolo:
4D CONFOCAL MICROSCOPY FOR VISUALIZATION OF BONE REMODELING
Autore:
KONIJN GA; VARDAXIS NJ; BOON ME; KOK LP; RIETVELD DC; SCHUT JJ;
Indirizzi:
LEIDEN CYTOL & PATHOL LAB,POSTBUS 16084 NL-2301 GB LEIDEN NETHERLANDS LEIDEN CYTOL & PATHOL LAB NL-2301 GB LEIDEN NETHERLANDS ROYAL MELBOURNE INST TECHNOL,DEPT MED LAB SCI BUNDOORA VIC AUSTRALIA UNIV GRONINGEN,INST THEORET PHYS GRONINGEN NETHERLANDS LEIDEN UNIV HOSP,DEPT ORTHOPAED SURG LEIDEN NETHERLANDS
Titolo Testata:
Pathology research and practice
fascicolo: 6, volume: 192, anno: 1996,
pagine: 566 - 572
SICI:
0344-0338(1996)192:6<566:4CMFVO>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
3-DIMENSIONAL RECONSTRUCTION; FLUORESCENCE MICROSCOPY; FRACTURES; SMEARS; GRAFTS;
Keywords:
CONFOCAL MICROSCOPY; BONE GRAFT; BONE REMODELING; COMPUTER-ASSISTED 3D AND 4D RECONSTRUCTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
G.A. Konijn et al., "4D CONFOCAL MICROSCOPY FOR VISUALIZATION OF BONE REMODELING", Pathology research and practice, 192(6), 1996, pp. 566-572

Abstract

Until recently it was very time consuming and difficult to make three-dimensional (3D) images of newly formed bone. With the advent of confocal technologies and increased computer power 3D imaging is greatly facilitated. In this paper we demonstrate that enhanced confocal visualisation of newly formed bone is possible when bone is labelled in vivosequentially with two osteotropic markers (xylenol orange and tetracycline). Computer-assisted reconstruction of the confocal optical sections was achieved through the use of the CONVEX Application Visualisation System (AVS). The computerised image data provides the researcher with ample flexibility in displaying the results. It was found that CSLM combined with AVS is excellent for visualising the remodelling process in three and four dimensions, in which the fourth dimension is time. With this approach visualised bone remodelling has become possible in a manner not easily achieved by other techniques.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/09/20 alle ore 22:58:00