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Titolo:
DECLINING PREVALENCE OF CERVICOVAGINAL HUMAN PAPILLOMAVIRUS INFECTIONWITH AGE IS INDEPENDENT OF OTHER RISK-FACTORS
Autore:
BURK RD; KELLY P; FELDMAN J; BROMBERG J; VERMUND SH; DEHOVITZ JA; LANDESMAN SH;
Indirizzi:
ALBERT EINSTEIN COLL MED,DEPT PEDIAT,ULLMANN BLDG,ROOM 625,1300 MORRIS PK AVE BRONX NY 10461 ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL BRONX NY 00000 ALBERT EINSTEIN COLL MED,DEPT OBSTET & GYNECOL BRONX NY 00000 SUNY HLTH SCI CTR,DEPT MED BROOKLYN NY 11203 SUNY HLTH SCI CTR,DEPT PREVENT MED & COMMUNITY HLTH BROOKLYN NY 11203 UNIV MICHIGAN,SCH PUBL HLTH,DEPT BIOSTAT ANN ARBOR MI 48109 NIAID,DIV AIDS,NIH BETHESDA MD 20892
Titolo Testata:
Sexually transmitted diseases
fascicolo: 4, volume: 23, anno: 1996,
pagine: 333 - 341
SICI:
0148-5717(1996)23:4<333:DPOCHP>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
GENITAL HUMAN PAPILLOMAVIRUS; HUMAN-IMMUNODEFICIENCY-VIRUS; CYTOLOGICALLY NORMAL WOMEN; POLYMERASE CHAIN-REACTION; CERVICAL-CANCER; SEXUAL-BEHAVIOR; NEW-MEXICO; HPV; DETERMINANTS; NEOPLASIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
46
Recensione:
Indirizzi per estratti:
Citazione:
R.D. Burk et al., "DECLINING PREVALENCE OF CERVICOVAGINAL HUMAN PAPILLOMAVIRUS INFECTIONWITH AGE IS INDEPENDENT OF OTHER RISK-FACTORS", Sexually transmitted diseases, 23(4), 1996, pp. 333-341

Abstract

Background and Objectives: Human papillomavirus (HPV) infection of the female genital tract is the most common sexually transmitted disease, Although the prevalence of HPV in women without detectable cervical disease has been shown to decline with increasing age, the relationship to sexual behavior has not been investigated. Goal: To identify riskfactors for, and associated with the age-dependent decline in, genital HPV infection in women, Study Design: The prevalence of HPV was determined in a cohort of 439 sexually active inner-city women between theages of 18 and 50 years recruited in Brooklyn, New York, Cervicovaginal cells were collected by lavage, and HPV was detected by low-stringent Southern blot hybridization, Results: The prevalence of HPV infection ranged from 36% in women younger than 25 years of age to 2.8% in women 45 years or older, Logistic regression analysis identified an increased risk for cervical HPV infection to be independently associated with number of sex partners in the past year (odds ratio [OR], 1.04 peryearly increase in age; 95% confidence interval [CI], 1.00 to 1.08), younger age (OR, 0.92 per year increase in age; 95% CI, 0.88 to 0.95),and not living with partner (OR, 2.28; 95% CI, 1.40 to 4.22), Conclusions: The lower prevalence of HPV infection in older women compared toyounger women was found to be independent of sexual behavior, These results suggest that a biologic effect, such as HPV immunity acquired over time and with multiple exposures, may mediate the inverse relationship between age and HPV prevalence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/21 alle ore 07:49:07