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Titolo:
LITHOFIBRIN - A NEW REMARKABLY STABLE SUBSTANCE FOUND IN RENAL STONES
Autore:
OHMAN S; LARSSON L;
Indirizzi:
LINKOPING UNIV,FAC HLTH SCI,DEPT CLIN CHEM S-58185 LINKOPING SWEDEN
Titolo Testata:
Acta chemica Scandinavica
fascicolo: 7, volume: 50, anno: 1996,
pagine: 633 - 636
SICI:
0904-213X(1996)50:7<633:L-ANRS>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
S. Ohman e L. Larsson, "LITHOFIBRIN - A NEW REMARKABLY STABLE SUBSTANCE FOUND IN RENAL STONES", Acta chemica Scandinavica, 50(7), 1996, pp. 633-636

Abstract

Besides inorganic constituents, renal stones contain organic matter known as stone matrix. We have examined such matrix obtained from stones that had been crushed by extracorporeal shock-wave lithotripsy, in order to determine its chemical properties. Morphologically, the matrixwas composed of fibers of different colors, most of them exhibiting autofluorescence. Proteins or any other well-known biochemical materialwere not present. It was remarkably stable against chemical degradation, and could not be dissolved in hot concentrated acids or bases or any common organic solvent. Elementary analysis revealed carbon (60.8%), oxygen (26.9%), nitrogen (7.6%), hydrogen (5.3%) and sulfur (0.77%) to be present. Furthermore, X-ray emission spectroscopy revealed the presence of titanium and chromium. Solid-phase C-13 NMR spectroscopy revealed the presence of aromatic and aliphatic carbon as well as carbonbound to O and/or N. The material was paramagnetic. All findings indicated the matrix to be composed of a new class of organic compound, probably a polyaromatic heterocyclic organic material. We welcome suggestions on further methods that can ultimately elucidate the nature of lithofibrins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 04:07:03