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Titolo:
BONE TURNOVER AND MINERAL METABOLISM IN THE LAST TRIMESTER OF PREGNANCY - EFFECT OF MULTIPLE GESTATION
Autore:
OKAH FA; TSANG RC; SIERRA R; BRADY KK; SPECKER BL;
Indirizzi:
UNIV CINCINNATI,MED CTR,PERINATAL RES INST,CHILDRENS HOSP RES FDN,231BETHESDA AVE CINCINNATI OH 45267 UNIV CINCINNATI,MED CTR,PERINATAL RES INST,CHILDRENS HOSP RES FDN CINCINNATI OH 45267 GOOD SAMARITAN HOSP,DEPT OBSTET CINCINNATI OH 00000
Titolo Testata:
Obstetrics and gynecology
fascicolo: 2, volume: 88, anno: 1996,
pagine: 168 - 173
SICI:
0029-7844(1996)88:2<168:BTAMMI>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
VITAMIN-D METABOLISM; OSTEOPOROSIS; MARKERS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
F.A. Okah et al., "BONE TURNOVER AND MINERAL METABOLISM IN THE LAST TRIMESTER OF PREGNANCY - EFFECT OF MULTIPLE GESTATION", Obstetrics and gynecology, 88(2), 1996, pp. 168-173

Abstract

Objective: To test the hypothesis that maternal bone turnover and mineral stress are greater in multiple pregnancy than in singleton pregnancy. Methods: We measured serum markers of bone turnover and mineral stress in 17 multiple and 30 singleton pregnancies during the third trimester. Results: Serum 25(OH) vitamin D, a marker of vitamin D intake,was higher (61 +/- 5 versus 39 +/- 2 ng/mL, P <.001), and 1,25(OH)(2)vitamin D was lower (50 [95% confidence interval (CD 24-102] versus 64 pg/mL [95% CI 30-135], P = .03) in multiple than in singleton pregnancy. Carboxyterminal telopeptide of type I collagen, a marker of bone resorption, increased with gestational duration and was higher in multiple gestation (5.8 [95% CI 3.3-10.1] versus 4.4 ng/mL [95% CI 2.5-7.8], P = .005). Carboxyl-terminal propeptide of type 1 procollagen, a marker of bone formation, increased with gestational duration and was not different between groups (110 [95% CI 36-337] versus 99 ng/mL [95% CI 34-286], P = .5). Calcitonin increased with gestational duration andwas not different between groups (7.0 [95% CI 3.7-13.0] versus 7.8 pg/mL [95% CI 4.0-15.4], P = .37). Parathyroid hormone was not differentbetween groups and decreased with increasing maternal age. Conclusion: Bone turnover indices increased with gestational duration. The bone resorption index was greater in multiple than in singleton gestation. Serum 25(OH) vitamin D was greater and 1,25(OH)(2) vitamin D was lowerin multiple gestation, presumably because of greater consumption of vitamin D and minerals by women carrying more than one fetus.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 10:29:37