Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
CIRCADIAN RHYTHMICITY OF TRYPTOPHAN-HYDROXYLASE IN THE MARINE DINOFLAGELLATE GONYAULAX-POLYEDRA STEIN AND THE ROLE OF TRYPTOPHAN HYDROXYLATION IN BIOLUMINESCENCE
Autore:
BURKHARDT S; HARDELAND R;
Indirizzi:
UNIV GOTTINGEN,INST ZOOL 1,BERLINER STR 28 D-37073 GOTTINGEN GERMANY UNIV GOTTINGEN,INST ZOOL 1 D-37073 GOTTINGEN GERMANY
Titolo Testata:
Comparative biochemistry and physiology. B. Comparative biochemistry
fascicolo: 3, volume: 115, anno: 1996,
pagine: 411 - 416
SICI:
0305-0491(1996)115:3<411:CROTIT>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
XENOPUS-LAEVIS; MELATONIN; INDOLEAMINES; RETINA;
Keywords:
BIOLUMINESCENCE; CIRCADIAN RHYTHMS; DINOFLAGELLATES; GONYAULAX; INDOLEAMINES; MELATONIN; 5-METHOXYTRYPTAMINE; PROTON TRANSLOCATION; TRYPTOPHAN HYDROXYLASE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
S. Burkhardt e R. Hardeland, "CIRCADIAN RHYTHMICITY OF TRYPTOPHAN-HYDROXYLASE IN THE MARINE DINOFLAGELLATE GONYAULAX-POLYEDRA STEIN AND THE ROLE OF TRYPTOPHAN HYDROXYLATION IN BIOLUMINESCENCE", Comparative biochemistry and physiology. B. Comparative biochemistry, 115(3), 1996, pp. 411-416

Abstract

In the bioluminescent dinoflagellate Gonyaulax polyedra, tryptophan hydroxylase activity exhibits a circadian rhythm of high amplitude, which persists in constant light. The maximum is found in the middle of photophase. Melatonin or exposure to a decreased temperature (15 degrees C), a treatment leading to melatonin accumulation, suppresses tryptophan hydroxylase activity. 5-Hydroxytryprophan, but not tryptophan, stimulates bioluminescence. The dosage dependence of this effect of 5-hydroxytryptophan is similar to that of its metabolite serotonin. These actions seem to be due to the further conversion to a much more potentmetabolite, 5-methoxytryptamine. Inhibition of tryptophan hydroxylaseby p-chlorophenylalanine, p-fluorophenylalanine or 5-fluorotryptophandecreases light emission. This inhibition can be overcome by additionof various indolic metabolites originating from the tryptophan hydroxylation pathway, in particular, 5-hydroxycryptophan, serotonin, melatonin and 5-methoxytryptamine. Copyright (C) 1996 Elsevier Science Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/07/20 alle ore 10:27:34