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Titolo:
NEOADJUVANT CHEMOTHERAPY IN UTERINE PAPILLARY SEROUS CARCINOMA
Autore:
RESNIK E; TAXY JB;
Indirizzi:
LUTHERAN GEN HOSP,DEPT OBSTET & GYNECOL,DIV GYNECOL ONCOL PARK RIDGE IL 60068 LUTHERAN GEN HOSP,DEPT PATHOL,CANC CARE CTR PARK RIDGE IL 60068
Titolo Testata:
Gynecologic oncology
fascicolo: 1, volume: 62, anno: 1996,
pagine: 123 - 127
SICI:
0090-8258(1996)62:1<123:NCIUPS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGESTERONE-RECEPTOR CONTENT; ENDOMETRIAL CARCINOMA; IMMUNOHISTOCHEMICAL EVALUATION; CYCLOPHOSPHAMIDE; DOXORUBICIN; CISPLATIN; ESTROGEN; SURVIVAL; CANCER; UPSC;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
E. Resnik e J.B. Taxy, "NEOADJUVANT CHEMOTHERAPY IN UTERINE PAPILLARY SEROUS CARCINOMA", Gynecologic oncology, 62(1), 1996, pp. 123-127

Abstract

Uterine papillary serous carcinoma (UPSC) is an aggressive variant ofendometrial cancer that frequently imitates serous carcinoma of the ovary in its clinical presentation and histologic appearance. Unlike the ovarian lesion, however, it is known to be particularly resistant tochemotherapy. A patient with a putative diagnosis of unresectable Stage IV ovarian cancer was treated with three cycles of neoadjuvant chemotherapy containing paclitaxel and carboplatin. After a remarkable response, interval cytoreductive surgery was performed. A primary endometrial tumor with the pathologic features of UPSC was found. To our knowledge, the use of paclitaxel-containing chemotherapy in UPSC has not been reported. We suggest that this therapy might be useful in the treatment of patients with advanced uterine papillary serous carcinoma, aswell as in an adjuvant setting. (C) 1996 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/09/20 alle ore 13:36:35