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Titolo:
UPTAKE OF L-LEUCINE BY TROUT RED-BLOOD-CELLS AND PERIPHERAL LYMPHOCYTES
Autore:
GALLARDO MA; ALBI JL; SANCHEZ J;
Indirizzi:
UNIV BARCELONA,FAC BIOL,DEPT FISIOL,AVE DIAGONAL 645 E-08028 BARCELONA SPAIN UNIV BARCELONA,FAC BIOL,DEPT FISIOL E-08028 BARCELONA SPAIN
Titolo Testata:
The Journal of membrane biology
fascicolo: 1, volume: 152, anno: 1996,
pagine: 57 - 63
SICI:
0022-2631(1996)152:1<57:UOLBTR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMINO-ACID-TRANSPORT; L-ALANINE UPTAKE; TAURINE TRANSPORT; HEPATOCYTES; SYSTEMS; ASC; ERYTHROCYTES;
Keywords:
LEUCINE UPTAKE; RED BLOOD CELL (RBC); PERIPHERAL BLOOD LYMPHOCYTES (PBL); L SYSTEM; TROUT (SALMO TRUTTA);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
24
Recensione:
Indirizzi per estratti:
Citazione:
M.A. Gallardo et al., "UPTAKE OF L-LEUCINE BY TROUT RED-BLOOD-CELLS AND PERIPHERAL LYMPHOCYTES", The Journal of membrane biology, 152(1), 1996, pp. 57-63

Abstract

The uptake of L-leucine by trout red blood cells and peripheral lymphocytes has been analyzed. The present study shows two functionally different Na+-independent systems for apolar branched-chain amino acids. They are designated as L systems because they share some properties with the mammalian L system. The carrier present in red blood cells has low K-m values, is trans-stimulable and not stereospecific for leucineuptake; on the other hand, the system present in lymphocytes is stereospecific for leucine uptake and trans-inhibitable. Both carriers are pH sensitive in a similar fashion at low pi-Is, but there are important differences at higher pH values (above neutrality). These propertiesare compared with these of the ase systems previously reported in these cells.

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Documento generato il 28/01/21 alle ore 08:03:26