Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
ARTERIAL AND CARDIOPULMONARY BAROREFLEXES IN 60-YEAR-OLD TO 69-YEAR-OLD VS 18-YEAR-OLD TO 36-YEAR-OLD HUMANS
Autore:
SHI XR; GALLAGHER KM; WELCHOCONNOR RM; FORESMAN BH;
Indirizzi:
UNIV N TEXAS,HLTH SCI CTR,DEPT PHYSIOL,3500 CAMP BOWIE BLVD FT WORTH TX 76107 UNIV N TEXAS,HLTH SCI CTR,DEPT MED FT WORTH TX 76107
Titolo Testata:
Journal of applied physiology
fascicolo: 6, volume: 80, anno: 1996,
pagine: 1903 - 1910
SICI:
8750-7587(1996)80:6<1903:AACBI6>2.0.ZU;2-I
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOREARM VASCULAR-RESISTANCE; CENTRAL VENOUS-PRESSURE; BODY POSITIVE PRESSURE; BLOOD-PRESSURE; SYMPATHETIC ACTIVITY; CAROTID BAROREFLEX; VASOCONSTRICTOR RESPONSES; NEUROHUMORAL RESPONSES; ORTHOSTATIC STRESS; AGED RATS;
Keywords:
AGING; CENTRAL HYPOVOLEMIA; CENTRAL VENOUS PRESSURE; FOREARM VASCULAR RESISTANCE; GAIN; INTERACTION; LOWER BODY NEGATIVE PRESSURE; PERIPHERAL VENOUS PRESSURE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
48
Recensione:
Indirizzi per estratti:
Citazione:
X.R. Shi et al., "ARTERIAL AND CARDIOPULMONARY BAROREFLEXES IN 60-YEAR-OLD TO 69-YEAR-OLD VS 18-YEAR-OLD TO 36-YEAR-OLD HUMANS", Journal of applied physiology, 80(6), 1996, pp. 1903-1910

Abstract

This study was designed to test the hypothesis that aging diminished baroreflex function during central hypovolemia. Eleven healthy young and eleven older (age 60-69 yr) individuals were assessed by using heart rate (HR) and mean arterial pressure (MAP) responses to neck pressure and suction during rest and lower body negative pressure (LBNP) of -15 Torr. The slope of forearm vascular resistance to central venous pressure during low-level LBNP was assessed as the index of cardiopulmonary baroreflex sensitivity. Baseline cardiovascular variables were notsignificantly different between the groups. In addition, there was nogroup difference in cardiopulmonary baroreflex (-3.6 vs. -3.7 units/mmHg for young vs. older, respectively) or carotid baroreflex (-0.39 vs. -0.35 beats . min(-1) . mmHg(-1) and -0.26 vs. -0.35 mmHg/mmHg, for young vs. older, respectively) sensitivity. LBNP did not affect eitherHR or MAP, whereas it decreased CVP and increased FVR in both groups. LBNP significantly augmented the carotid-HR (-0.47 +/- 0.03 beats . min(-1) . mmHg(-1)) and carotid-MAP (-0.42 +/- 0.04 mmHg/mmHg) reflex gains in the young subjects only. We concluded that there was no difference in the discrete baroreflex function between the two age groups; however, the interaction of cardiopulmonary baroreceptors with carotid baroreflex function was absent in the older subjects, suggesting that the central integration of afferent neural inputs from the discrete baroreceptors was altered with aging.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:36:38