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Titolo:
SPONDYLODISKITIS DUE TO CANDIDA-ALBICANS - REPORT OF 2 PATIENTS WHO WERE SUCCESSFULLY TREATED WITH FLUCONAZOLE AND REVIEW OF THE LITERATURE
Autore:
HENNEQUIN C; BOUREE P; HIESSE C; DUPONT B; CHARPENTIER B;
Indirizzi:
HOP NECKER ENFANTS MALAD,MICROBIOL SERV,149 RUE SEVRES F-75015 PARIS FRANCE HOP BICETRE,SERV NEPHROL LE KREMLIN BICETR FRANCE HOP BICETRE,UNITE PARASITOL MYCOL LE KREMLIN BICETR FRANCE HOP LOUIS PASTEUR,SERV MALAD INFECT & TROP PARIS FRANCE
Titolo Testata:
Clinical infectious diseases
fascicolo: 1, volume: 23, anno: 1996,
pagine: 176 - 178
SICI:
1058-4838(1996)23:1<176:SDTC-R>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
VERTEBRAL OSTEOMYELITIS; JOINT INFECTIONS; ADULTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
18
Recensione:
Indirizzi per estratti:
Citazione:
C. Hennequin et al., "SPONDYLODISKITIS DUE TO CANDIDA-ALBICANS - REPORT OF 2 PATIENTS WHO WERE SUCCESSFULLY TREATED WITH FLUCONAZOLE AND REVIEW OF THE LITERATURE", Clinical infectious diseases, 23(1), 1996, pp. 176-178

Abstract

We report the cases of two patients with spondylodiskitis due to Candida albicans who were successfully treated with fluconazole. On the basis of findings from these cases and a review of 52 mycologically proven cases in the literature, we describe the main characteristics of candidal spondylodiskitis. In 60% of the cases, candidal spondylodiskitis was a late complication of candidemia (mean delay, 5.2 months); it was determined to be a complication on the basis of the results of previously positive blood cultures (19 cases), and it was presumed to be acomplication in iv drug addicts (12 cases). As spondylodiskitis can be a late complication of candidemia, all episodes of candidemia shouldbe treated with systemic antifungal agents, Clinical and radiologicalsigns of candidal spondylodiskitis were nonspecific, Any bone or joint symptoms in a patient who has had candidemia should be considered tobe of fungal origin at the time of presentation, The definitive diagnosis of candidal spondylodiskitis was made on the basis of the resultsof percutaneous puncture in 26 of 30 cases, The overall prognosis forpatients with candidal spondylodiskitis was good, with the full recovery rate ranging from 67% to 100%. The preliminary results of treatingcandidal spondylodiskitis with triazole derivatives, particularly fluconazole, were satisfactory; there was excellent tolerance of this drug.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 08:35:50