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Titolo:
INFLUENCE OF SELECTIVE NERVE-FIBER BLOCKS ON ARGON LASER-INDUCED THERMAL PAIN IN THE HUMAN SKIN
Autore:
GRONROOS M; REUNALA T; PERTOVAARA A;
Indirizzi:
HELSINKI UNIV,CENT HOSP,DEPT DERMATOL HELSINKI FINLAND HELSINKI UNIV,CENT HOSP,DEPT DERMATOL HELSINKI FINLAND HELSINKI UNIV,INST BIOMED,DEPT PHYSIOL FIN-00014 HELSINKI FINLAND UNIV TURKU,INST BIOMED,DEPT PHYSIOL SF-20520 TURKU FINLAND
Titolo Testata:
Neuroscience letters
fascicolo: 2, volume: 211, anno: 1996,
pagine: 143 - 145
SICI:
0304-3940(1996)211:2<143:IOSNBO>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPATIAL SUMMATION; TOPICAL CAPSAICIN; STIMULUS AREA; THRESHOLDS; RESPONSES; HEAT; PULSES;
Keywords:
CUTANEOUS PAIN; ARGON LASER; CAPSAICIN; SPATIAL SUMMATION; HEAT PAIN THRESHOLD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
M. Gronroos et al., "INFLUENCE OF SELECTIVE NERVE-FIBER BLOCKS ON ARGON LASER-INDUCED THERMAL PAIN IN THE HUMAN SKIN", Neuroscience letters, 211(2), 1996, pp. 143-145

Abstract

Influence of selective nerve fiber blocks on cutaneous pain induced by short argon laser pulses was studied in healthy humans. The minimal energy per surface area needed to produce a pain sensation was lower with a larger stimulus surface indicating spatial summation. Both compression of the peripheral nerve innervating the stimulus site (A-fiber block) and prolonged topical treatment of the stimulus site with 1% capsaicin (a predominant block of nociceptive C-fibers) produced an elevation of the pain threshold. Prolonged capsaicin treatment produced significantly higher pain thresholds than the compression block. Magnitude of the pain threshold elevation induced by nerve blocks varied depending on the area of the stimulus surface. Especially following prolonged capsaicin treatment, pain threshold elevations tended to be smaller with the larger area of the stimulus surface suggesting an enhanced spatial summation effect. Tactile thresholds were significantly elevated only by the compression block. The results indicate that nociceptive C-fibers have a significant contribution to the threshold sensation of pain induced by argon laser. Moreover, following impairment of function in nociceptive C-fibers, the spatial summation of argon laser-induced pain tends to be enhanced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 20:54:43