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Titolo:
CONCENTRATIONS OF MERCURY, CADMIUM AND LEAD IN BRAIN AND KIDNEY OF 2ND-TRIMESTER FETUSES AND INFANTS
Autore:
LUTZ E; LIND B; HERIN P; KRAKAU I; BUI TH; VAHTER M;
Indirizzi:
KAROLINSKA INST,INST ENVIRONM MED S-10401 STOCKHOLM SWEDEN KAROLINSKA INST,INST ENVIRONM MED S-10401 STOCKHOLM SWEDEN KAROLINSKA INST,DANDERYD HOSP,DEPT PEDIAT S-18288 DANDERYD SWEDEN KAROLINSKA HOSP,RES CTR GEN MED S-10401 STOCKHOLM SWEDEN KAROLINSKA INST,KAROLINSKA HOSP,DEPT CLIN GENET S-10401 STOCKHOLM SWEDEN
Titolo Testata:
Journal of trace elements in medicine and biology
fascicolo: 2, volume: 10, anno: 1996,
pagine: 61 - 67
SICI:
0946-672X(1996)10:2<61:COMCAL>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
DENTAL AMALGAM FILLINGS; DEATH SYNDROME; EXPOSURE; WOMEN; ZINC;
Keywords:
TOXIC METALS; EXPOSURE; TISSUES; DEVELOPMENT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
E. Lutz et al., "CONCENTRATIONS OF MERCURY, CADMIUM AND LEAD IN BRAIN AND KIDNEY OF 2ND-TRIMESTER FETUSES AND INFANTS", Journal of trace elements in medicine and biology, 10(2), 1996, pp. 61-67

Abstract

The concentrations of mercury (Hg), cadmium (Cd) and lead (Pb) in brain (cerebrum) and kidney during fetal (second trimester terminations or abortions, n=20) and postnatal (infants deceased before three monthsof age, n=15) development have been studied. Information on possible sources of exposure was obtained from the mothers of the fetuses, but not from those of the infants. The median concentration of Hg in the brain was 4 mu g/kg wet weight in both fetuses and infants (total rangeless than or equal to 2-23 mu g/kg). The concentrations of Hg in the kidneys were significantly higher than in brain, median of Hg 6 mu g/kg (range less than or equal to 5-34 mu g/kg) in fetuses and 10 mu g/kg(less than or equal to 7-37) in infants. There was a tendency of increasing concentration of Hg in the fetal kidney, but not in the brain, with increasing number of amalgam fillings in the mothers. The concentration of Cd in the brain was less than 1 mu g/kg in most cases, both in fetuses and infants. The concentration of Cd in the kidneys was significantly higher, with a median of about 2 mu g/kg (1-8 mu g/kg) in both groups. There was no detectable association between tissue Cd concentrations and the smoking habits of the mothers. The concentration ofPb in brain was below 10 mu g/kg in most cases. In the kidneys, the concentrations of Pb were significantly higher, with a median of 12 mu g/kg in the fetuses (range less than or equal to 6-20 mu kg/g) and 15 mu g/kg (less than or equal to 9-36 mu g/g) in the infants. In general, the concentrations of Cd and Pb were lower than in previously reported studies.

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Documento generato il 04/12/20 alle ore 22:40:32