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Titolo:
RETROSPECTIVE ANALYSIS OF THE TREATMENT OF PATIENTS WITH SMALL-CELL LUNG-CANCER SHOWING POOR PERFORMANCE STATUS
Autore:
SAKURAGI T; OSHITA F; NAGASHIMA S; KASAI T; KURATA T; FUKUDA M; YAMAMOTO N; OHE Y; TAMURA T; EGUCHI K; SHINKAI T; SAIJO N;
Indirizzi:
NATL CANC CTR,RES INST,DIV PHARMACOL,CHUO KU,1-1 TSUKIJI 5 CHOME TOKYO 104 JAPAN NATL CANC CTR,DIV MED ONCOL TOKYO JAPAN
Titolo Testata:
Japanese Journal of Clinical Oncology
fascicolo: 3, volume: 26, anno: 1996,
pagine: 128 - 133
SICI:
0368-2811(1996)26:3<128:RAOTTO>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
PROGNOSTIC FACTORS; CHEMOTHERAPY;
Keywords:
SMALL CELL LUNG CANCER; POOR PERFORMANCE STATUS; CHEMORADIOTHERAPY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
10
Recensione:
Indirizzi per estratti:
Citazione:
T. Sakuragi et al., "RETROSPECTIVE ANALYSIS OF THE TREATMENT OF PATIENTS WITH SMALL-CELL LUNG-CANCER SHOWING POOR PERFORMANCE STATUS", Japanese Journal of Clinical Oncology, 26(3), 1996, pp. 128-133

Abstract

To assess the feasibility of treatments for patients with small cell lung cancer (SCLC) showing a poor performance status (PS, Eastern Cooperative Oncology Group; ECOG 3 or 4), we retrospectively reviewed the outcome for 13 SCLC patients showing poor PS treated at the National Cancer Center Hospital between January 1984 and May 1994. The main factors which contributed to poor prognosis were superior vena cava (SVC) syndrome, massive pleural effusion, tracheal stenosis due to lymph node swelling, pericardial effusion and pulmonary fibrosis (causing dyspnea in combination), brain metastasis resulting in neurological disturbance, cachexia, Eaton-Lambert syndrome causing muscle weakness, retroperitoneal lymph node metastasis causing abdominal pain, peritoneal effusion due to abdominal lymph node swelling, vertebral metastasis causing paraplegia, and dermatomyositis/polymyositis (DM/PM) causing muscleweakness. All of the patients received chemotherapy with or without radiotherapy. The PS of 8 patients improved with treatment, but no improvement was seen in 5. We analyzed these 13 patients and considered the treatments for those with poor PS. Chemo-radiotherapy was tolerable in SCLC patients showing PS 3, and improved their PS if severe conditions or combined disease did not arise concurrently. It was further suggested that PS 4 patients with severe conditions or combined disease should not be given the treatments.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/06/20 alle ore 01:59:11