Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EXERCISE-INDUCED CHANGES IN LOCAL CEREBRAL GLUCOSE-UTILIZATION IN THERAT
Autore:
VISSING J; ANDERSEN M; DIEMER NH;
Indirizzi:
UNIV COPENHAGEN,RIGSHOSP,DEPT NEUROL,BLEGDAMSVEJ 9 DK-2100 COPENHAGENDENMARK UNIV COPENHAGEN,PANUM INST,DEPT MED PHYSIOL DK-2200 COPENHAGEN N DENMARK UNIV COPENHAGEN,INST NEUROPATHOL COPENHAGEN DENMARK R HILLEROD CTY HOSP,DEPT PSYCHIAT HILLEROD DENMARK
Titolo Testata:
Journal of cerebral blood flow and metabolism
fascicolo: 4, volume: 16, anno: 1996,
pagine: 729 - 736
SICI:
0271-678X(1996)16:4<729:ECILCG>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; DYNAMIC EXERCISE; METABOLIC-RATE; RUNNING RATS; BRAIN; REST; DOGS;
Keywords:
AUTORADIOGRAPHY; BRAIN GLUCOSE METABOLISM; 2-DEOXYGLUCOSE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
J. Vissing et al., "EXERCISE-INDUCED CHANGES IN LOCAL CEREBRAL GLUCOSE-UTILIZATION IN THERAT", Journal of cerebral blood flow and metabolism, 16(4), 1996, pp. 729-736

Abstract

In exercise, little is known about local cerebral glucose utilization(LCGU), which is an index of functional neurogenic activity. We measured LCGU in resting and running (approximate to 85% of maximum O-2 uptake) rats (n = 7 in both groups) previously equipped with a tail artery catheter. LCGU was measured quantitatively from 2-deoxy-D-[1-C-14]glucose autoradiographs. During exercise, total cerebral glucose utilization (TCGU) increased by 38% (p < 0.005), LCGU increased (p < 0.05) inareas involved in motor function (motor cortex 39%, cerebellum approximate to 110%, basal ganglia approximate to 30%, substantia nigra approximate to 37%, and in the following nuclei: subthalamic 47%, posterior hypothalamic 74%, red 61%, ambiguus 43%, pontine 61%), areas involved in sensory function (somatosensory 27%, auditory 32%, and visual cortex 42%, thalamus approximate to 75%, and in the following nuclei: Darkschewitsch 22%, cochlear 51%, vestibular 30%, superior olive 23%, cuneate 115%), areas involved in autonomic function (dorsal raphe nucleus30%, and areas in the hypothalamus approximate to 35%, amygdala approximate to 35%, and hippocampus 29%), and in white matter of the corpuscallosum (36%) and cerebellum (52%). LCGU did not change with exercise in prefrontal and frontal cortex, cingulum, inferior olive, nucleus of solitary tract and median raphe, lateral septal and interpenduncular nuclei, or in areas of the hippocampus, amygdala, and hypothalamus. Glucose utilization did not decrease during exercise in any of the studied cerebral regions. In summary, heavy dynamic exercise increases TCGU acid evokes marked differential changes in LCGU. The findings provide clues to the cerebral areas that participate in the large motor, sensory, and autonomic adaptation occurring in exercise.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 07:20:28