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Titolo:
DUCT-ECTATIC TYPE OF MUCIN-PRODUCING TUMOR OF THE PANCREAS - NEW CONCEPT OF PANCREATIC NEOPLASIA
Autore:
KIMURA W; SASAHIRA N; YOSHIKAWA T; MUTO T; MAKUUCHI M;
Indirizzi:
UNIV TOKYO,FAC MED,DEPT SURG 1,BUNKYO KU,7-3-1 HONGO TOKYO 113 JAPAN UNIV TOKYO,FAC MED,DEPT SURG 2 TOKYO 113 JAPAN
Titolo Testata:
Hepato-gastroenterology
fascicolo: 9, volume: 43, anno: 1996,
pagine: 692 - 709
SICI:
0172-6390(1996)43:9<692:DTOMTO>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
CYSTIC NEOPLASMS; CYTOLOGIC EXAMINATION; LATENT MALIGNANCY; DIAGNOSIS; CYSTADENOCARCINOMA; ADENOCARCINOMA; CYSTADENOMA; CARCINOMA; ECTASIA; JUICE;
Keywords:
DUCT CELL CARCINOMA; MUCINOUS CYSTADENOCARCINOMA; MUCIN-PRODUCING TUMOR OF THE PANCREAS;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
144
Recensione:
Indirizzi per estratti:
Citazione:
W. Kimura et al., "DUCT-ECTATIC TYPE OF MUCIN-PRODUCING TUMOR OF THE PANCREAS - NEW CONCEPT OF PANCREATIC NEOPLASIA", Hepato-gastroenterology, 43(9), 1996, pp. 692-709

Abstract

Backgound/Aims: Although there have been recent reports of mucin-producing tumor of the pancreas, there has been no thorough clinicopathological analysis of a large number of cases. Materials and Methods: Two hundred forty four cases of mucin-producing tumor of the pancreas fromJapanese, European and American reports, together with 15 cases of our own, were analyzed clinicopathologically. Results: Mucin-producing tumor of the pancreas was found in 177 males and 82 females (M:F = 2.2:1). The mean age was 65.5 years. Jaundice, diabetes mellitus and a past history of pancreatitis were found in 15%-19% of the cases. The tumor was most frequently (62%) found in the head of the pancreas. Pathologically, hyperplasia or adenoma teas found in 58 cases, and adenocarcinoma in 160 cases. Five-year-survival rate by the Kaplan-Meier method was 82.6% in all of the cases and postoperative survival curve was much better in cases with this type of carcinoma than in cases with ordinary pancreatic duct cell carcinoma (5-year-survival rate: 82.6% vs 17.3%). Serum tumor markers such as CEA or CA 19-9 were not effective in differentiating between benign and malignant, or in determining the degree of cancerous spread, while cytology of the pancreatic juice and biopsy of the tumor could contribute to the diagnosis. Conclusions: Mucin-producing tumor has unique clinicopathological characteristics, such as the dilated main pancreatic duct or branches, dilatation of the orifice of the papilla of Vater, or good prognosis. Since a diagnosis for benign or malignant is very difficult in some cases, methods for distinguishing benign from malignant lesions or for determining cancerous spread, such us molecular biological techniques, should be established.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/11/20 alle ore 18:04:19