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Titolo:
HEMORRHEOLOGIC EFFECTS OF METABOLITES OF PENTOXIFYLLINE (TRENTAL(R))
Autore:
AMBRUS JL; STADLER S; KULAYLAT M;
Indirizzi:
BUFFALO GEN HOSP,DEPT INTERNAL MED,100 HIGH ST BUFFALO NY 14203
Titolo Testata:
Journal of medicine
fascicolo: 1-2, volume: 26, anno: 1995,
pagine: 65 - 75
SICI:
0025-7850(1995)26:1-2<65:HEOMOP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Keywords:
ASPIRIN; DRUG METABOLITES; PENTOXIFYLLINE; PLATELET AGGREGATION; RED BLOOD CELL DEFORMABILITY; TRENTAL(R);
Tipo documento:
Article
Natura:
Periodico
Citazioni:
NO
Recensione:
Indirizzi per estratti:
Citazione:
J.L. Ambrus et al., "HEMORRHEOLOGIC EFFECTS OF METABOLITES OF PENTOXIFYLLINE (TRENTAL(R))", Journal of medicine, 26(1-2), 1995, pp. 65-75

Abstract

Pentoxifylline (Trental(R)) is metabolized by red blood cells and theliver into seven metabolites. Metabolites I and V have significant hemorrheologic effects. They are both similar to pentoxifylline in theiractivity on red blood cell membrane fluidity. Metabolite I is more active than pentoxifylline in inhibiting ADP-induced platelet aggregation. Metabolite V is more active than pentoxifylline in inhibiting epinephrine-induced platelet aggregation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:51:04