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Titolo:
MONSTROUS, CRAB-LIKE HYPERTROPHY OF THE CEREBELLAR VERMIS AND ITS RELATIONSHIP WITH LHERMITTE-DUCLOS DISEASE - CASE-REPORT
Autore:
DELEON GA; GRANT JA; DARLING CF;
Indirizzi:
CHILDRENS MEM HOSP,DEPT PATHOL,BOX 17,2300 CHILDRENS PLAZA CHICAGO IL60614 CHILDRENS MEM HOSP,DIV NEUROSURG CHICAGO IL 60614 CHILDRENS MEM HOSP,DIV NEURORADIOL CHICAGO IL 60614 NORTHWESTERN UNIV,SCH MED CHICAGO IL 00000
Titolo Testata:
Journal of neurosurgery
fascicolo: 1, volume: 85, anno: 1996,
pagine: 157 - 162
SICI:
0022-3085(1996)85:1<157:MCHOTC>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
DYSPLASTIC GANGLIOCYTOMA; NEWBORN;
Keywords:
BRAIN NEOPLASM; CEREBELLAR HYPERTROPHY; CEREBRAL MALFORMATION; HAMARTOBLASTOMA; LHERMITTE-DUCLOS DISEASE; MEDULLOBLASTOMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
G.A. Deleon et al., "MONSTROUS, CRAB-LIKE HYPERTROPHY OF THE CEREBELLAR VERMIS AND ITS RELATIONSHIP WITH LHERMITTE-DUCLOS DISEASE - CASE-REPORT", Journal of neurosurgery, 85(1), 1996, pp. 157-162

Abstract

The case of an infant with a peculiar tumorous malformation of the cerebellum is described. The tumor apparently developed as an exophytic,hypertrophic sprout of the inferior vermis. It had a monstrous appearance resembling a crab, with a metameric body and multiple pairs of limbs attached to the folia of both cerebellar hemispheres. Histologically, the lesion was formed by poorly differentiated neuroepithelial cells without any evidence of organization into nuclei, cortex, or fascicles. Clinically, the tumor behaved in an indolent manner and did not regrow after subtotal surgical resection. Because of its gross appearance and its biological behavior, this unusual hamartoblastomatous growth is readily distinguished from medulloblastoma. The morphology of thecerebellum in Lhermitte-Duclos disease is reviewed, and a new interpretation of its basic structure is proposed. This and other known typesof cerebellar hypertrophy are different from the malformation in the present case.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/12/20 alle ore 14:58:07