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Titolo:
PLACENTAL HORMONES, GENOMIC IMPRINTING, AND MATERNAL-FETAL COMMUNICATION
Autore:
HAIG D;
Indirizzi:
HARVARD UNIV,MUSEUM COMPARAT ZOOL,26 OXFORD ST CAMBRIDGE MA 02138
Titolo Testata:
Journal of evolutionary biology
fascicolo: 3, volume: 9, anno: 1996,
pagine: 357 - 380
SICI:
1010-061X(1996)9:3<357:PHGIAM>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PARENT-OFFSPRING CONFLICT; HUMAN CHORIONIC SOMATOMAMMOTROPIN; HUMAN CORPUS-LUTEUM; PHILIP SIDNEY GAME; GROWTH-HORMONE; GENE DELETION; PREGNANCY; GONADOTROPIN; SUPPRESSION; GESTATION;
Keywords:
GENOMIC IMPRINTING; SIGNALING; INTRAGENOMIC CONFLICT; PARENT-OFFSPRING CONFLICT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
47
Recensione:
Indirizzi per estratti:
Citazione:
D. Haig, "PLACENTAL HORMONES, GENOMIC IMPRINTING, AND MATERNAL-FETAL COMMUNICATION", Journal of evolutionary biology, 9(3), 1996, pp. 357-380

Abstract

Placental hormones are produced by one genetic individual (the fetus)to act on the receptors of another genetic individual (the mother). Mothers are probably able to extract some information from placental hormones, but this information may be limited to a crude measure of fetal vigor. Placental hormones are most easily interpreted as fetal attempts to manipulate maternal metabolism for fetal benefit. An evolutionary model is presented for a hypothetical hormone that increases the nutrient content of maternal blood. The model predicts that, at an evolutionary equilibrium, the hormone will be produced solely by the motheror solely by the placenta, but not by both. If the gene for the hormone is subject to genomic imprinting, the paternally-derived allele will be active and the maternally-derived allele will be silent. Hormone production benefits the members of the mother's current litter at somecost to future litters. Therefore, paternity changes between litters increase the level of hormone production. On the other hand, offspringthat produce less of the hormone than litter-mates share the benefitsbut have lower costs. Therefore, multiple paternity within litters reduces the level of hormone production.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 18:51:45