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Titolo:
CHANGES IN THE SPECTRUM OF AIDS-DIAGNOSTI C DISEASES IN SPAIN
Autore:
CASTILLA J; GUTIERREZ A; NOGUER I;
Indirizzi:
CTR NACL EPIDEMIOL,INST SALUD CARLOS III,SINESIO DELGADO 6 E-28029 MADRID SPAIN MINIST SANIDAD & CONSUMO,PLAN NACL SOBRE SIDA MADRID SPAIN
Titolo Testata:
Medicina Clinica
fascicolo: 19, volume: 106, anno: 1996,
pagine: 730 - 733
SICI:
0025-7753(1996)106:19<730:CITSOA>2.0.ZU;2-X
Fonte:
ISI
Lingua:
SPA
Soggetto:
IMMUNODEFICIENCY-VIRUS-INFECTION; DEFINING CONDITIONS; CONTROLLED TRIAL; UNITED-STATES; DRUG-USERS; TUBERCULOSIS; ZIDOVUDINE; COMPLEX; RISK; HIV;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
31
Recensione:
Indirizzi per estratti:
Citazione:
J. Castilla et al., "CHANGES IN THE SPECTRUM OF AIDS-DIAGNOSTI C DISEASES IN SPAIN", Medicina Clinica, 106(19), 1996, pp. 730-733

Abstract

BACKGROUND: Since the late 1980s the use of prophylaxis against several AIDS-diagnostic diseases has been recommended. In order to detect the impact of these measures we analyzed the shifts in the spectrum of AIDS-diagnostic diseases in Spain. PATIENTS AND METHODS: AIDS cases (CDC-1987) among patients over 12 years of age diagnosed in Spain duringthe period 1988-1993 were studied. Number and percentage of annual AIDS cases corresponding to each reported AIDS-diagnostic disease were analyzed. Annual percentage trends were assessed by means of chi(2) trend test and logistic regression adjusting for possible changes in distribution by transmission category, sex, and age-group. RESULTS: Annualincidence in most of AIDS-defining diseases rose over the period 1988-1993, although the proportion of cases in which the respective conditions appeared as AIDS-diagnostic diseases exhibited declining trends (p < 0.05) in: invasive candidiasis, Herpes simplex virus infection, isosporidiasis, Pneumocystis carinii pneumonia, extrapulmonary tuberculosis, Salmonella (non-thyphoid) septicemia, HIV encephalopathy and wasting syndrome. Increases were observed in the proportion of Mycobacterium avium complex disease and progressive multifocal leukoencephalopathy (p < 0.05). CONCLUSIONS: Some shifts in the spectrum of diseases arenoted, which could be dued to primary prophylaxis. Efforts should be targeted to improve coverage and compliance, and to develope guidelines of prophylaxis against the remaining diseases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:23:31