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Titolo:
SIMULTANEOUS QUANTITATIVE-EVALUATION OF VISUAL-EVOKED RESPONSES AND BACKGROUND EEG ACTIVITY IN RAT - NORMATIVE DATA
Autore:
SARKADI A; INCZEFFY Z;
Indirizzi:
G RICHTER LTD,PHARMACOL RES CTR,CHEM WORKS,POB 27 H-1475 BUDAPEST 10 HUNGARY
Titolo Testata:
Journal of pharmacological and toxicological methods
fascicolo: 3, volume: 35, anno: 1996,
pagine: 145 - 151
SICI:
1056-8719(1996)35:3<145:SQOVRA>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
LATERAL GENICULATE-BODY; PETIT-MAL EPILEPSY; FREELY MOVING RATS; POTENTIALS; CLASSIFICATION; DRUGS;
Keywords:
VISUAL-EVOKED POTENTIAL; PHOTICALLY EVOKED AFTERDISCHARGE; QUANTITATIVE ELECTROENCEPHALOGRAPHY; DAYTIME VARIABILITY; RAT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
37
Recensione:
Indirizzi per estratti:
Citazione:
A. Sarkadi e Z. Inczeffy, "SIMULTANEOUS QUANTITATIVE-EVALUATION OF VISUAL-EVOKED RESPONSES AND BACKGROUND EEG ACTIVITY IN RAT - NORMATIVE DATA", Journal of pharmacological and toxicological methods, 35(3), 1996, pp. 145-151

Abstract

An integrated quantitative electroencephalography system (Phegra) forpharmacological and toxicological research in rat is described. Peak latencies and amplitudes of visual-evoked potentials, occurrence, duration, and linear excursions of photically evoked afterdischarges, ''activity,'' ''mobility,'' ''complexity'' of Hjorth, and absolute spectral powers of delta, theta, alpha, and beta frequency bands of background activity of visual cortex and frontal-visual leads were measured in freely moving rats. Counts of small and large movements were also registered. Data of baseline measurements performed in large amount of animals are presented. None of the parameters except the occurrence of photically evoked afterdischarge and the linear excursion of its averaged waveshape changed significantly in five measurements performed within six hours following the intraperitoneal and oral administration of two commonly used drug vehicles.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/09/20 alle ore 05:24:25