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Titolo:
FOCAL CEREBRAL PERFUSION DEFECTS DEMONSTRATED BY TC-99M-HEXAMETHYLPROPYLENEAMINE OXIME SPECT IN ELDERLY DEPRESSED-PATIENTS
Autore:
VASILE RG; SCHWARTZ RB; GARADA B; HOLMAN BL; ALPERT M; DAVIDSON PB; SCHILDKRAUT JJ;
Indirizzi:
HARVARD UNIV,DEACONESS HOSP,SCH MED,DEPT PSYCHIAT,1 DEACONESS RD,PALMER BAKER SPAN 4 BOSTON MA 02215 HARVARD UNIV,BRIGHAM & WOMENS HOSP,SCH MED,DEPT RADIOL BOSTON MA 02115
Titolo Testata:
PSYCHIATRY RESEARCH-NEUROIMAGING
fascicolo: 1, volume: 67, anno: 1996,
pagine: 59 - 70
SICI:
0925-4927(1996)67:1<59:FCPDDB>2.0.ZU;2-P
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON EMISSION TOMOGRAPHY; REGIONAL BRAIN-FUNCTION; BLOOD-FLOW; MAJOR DEPRESSION; MOOD DISORDERS; GLUCOSE-METABOLISM; TC-99M-HMPAO SPECT; ALZHEIMERS-DISEASE; IMP SPECT; ANATOMY;
Keywords:
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; AFFECTIVE DISORDER; AGING; GERIATRIC PSYCHIATRY; FRONTAL LOBE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
45
Recensione:
Indirizzi per estratti:
Citazione:
R.G. Vasile et al., "FOCAL CEREBRAL PERFUSION DEFECTS DEMONSTRATED BY TC-99M-HEXAMETHYLPROPYLENEAMINE OXIME SPECT IN ELDERLY DEPRESSED-PATIENTS", PSYCHIATRY RESEARCH-NEUROIMAGING, 67(1), 1996, pp. 59-70

Abstract

High resolution single photon emission computed tomography (SPECT) was used to evaluate regional cerebral blood flow (rCBF) in 14 acutely depressed elderly patients and 29 normal subjects. SPECT images of the two groups were randomized and blindly read. Foci of decreased radionuclide uptake were assessed by number and location. The total number ofrCBF defects per whole brain study was significantly greater in the depressed patients than in the normal subjects. A significantly greaternumber of rCBF defects was found most strikingly in the lateral frontal and less prominently in the lateral and medial temporal brain regions of the depressed patients.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/08/20 alle ore 06:25:32