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Titolo:
EFFECTS OF INCREASED INTRAABDOMINAL PRESSURE UPON INTRACRANIAL AND CEREBRAL PERFUSION-PRESSURE BEFORE AND AFTER VOLUME EXPANSION
Autore:
BLOOMFIELD GL; RIDINGS PC; BLOCHER CR; MARMAROU A; SUGERMAN HJ;
Indirizzi:
VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT GEN TRAUMA SURG,DIVGEN TRAUMA SURG RICHMOND VA 23298 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DEPT GEN TRAUMA SURG,DIVGEN TRAUMA SURG RICHMOND VA 23298 VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,DIV NEUROSURG RICHMOND VA 23298
Titolo Testata:
The journal of trauma, injury, infection, and critical care
fascicolo: 6, volume: 40, anno: 1996,
pagine: 936 - 941
Fonte:
ISI
Lingua:
ENG
Soggetto:
INCREASED INTRAABDOMINAL PRESSURE; BRAIN COMPRESSION; BLOOD-FLOW; ARTERIAL; LAPAROSCOPY; TRAUMA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
G.L. Bloomfield et al., "EFFECTS OF INCREASED INTRAABDOMINAL PRESSURE UPON INTRACRANIAL AND CEREBRAL PERFUSION-PRESSURE BEFORE AND AFTER VOLUME EXPANSION", The journal of trauma, injury, infection, and critical care, 40(6), 1996, pp. 936-941

Abstract

Objective: To study the effects of elevated intra-abdominal pressure (IAP) upon intracranial (ICP) and cerebral perfusion pressure (CPP) before and after intravascular volume resuscitation. Materials and Methods: Intra-abdominal pressure was increased in five anesthetized swine by inflating an intraperitoneal balloon until the IAP was 25 mm Hg above baseline, Intravascular volume was then expanded and finally abdominal decompression was performed. Changes in ICP and systemic and pulmonary hemodynamic parameters secondary to increasing IAP were measured,The effect upon CPP was derived from these measurements. PaO2 and PaCO2 were maintained relatively constant by increasing ventilatory rate. Measurements and Main Results: Elevated IAP significantly increased ICP (7.6 +/- 1.2 vs, 21.4 +/- 1.0), pleural pressure and central venouspressure; whereas cardiac index and CPP (82.2 +/- 6.3 vs, 62.0 +/- 10.0) decreased significantly, Intravascular volume expansion further significantly increased ICP (27.8 +/- 1.0), and significantly increased both mean arterial pressure (83.4 +/- 14.0 versus 103.4 +/- 8.9) and CPP (75.6 +/- 9.0). Abdominal decompression returned ICP (11.2 +/- 1.8)toward baseline and further increased CPP (79.8 +/- 9.7). Conclusions: Elevated IAP increases ICP and decreases CPP and cardiac index, Volume expansion further increases ICP yet improves CPP via its greater positive effect upon mean arterial pressure (p < analysis of variance, All measurements are mean +/- SEM in mm Hg).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 15:33:56