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Titolo:
SHORT-TERM ALL-CAUSE MORTALITY AND ITS DETERMINANTS IN ELDERLY MALE POPULATIONS IN FINLAND, THE NETHERLANDS, AND ITALY - THE FINE STUDY
Autore:
MENOTTI A; KROMHOUT D; NISSINEN A; GIAMPAOLI S; SECCARECCIA F; FESKENS E; PEKKANEN J; TERVAHAUTA M;
Indirizzi:
NATL INST PUBL HLTH & ENVIRONM PROTECT,RIVM,PUBL HLTH RES DIV,POB 1 3720 BA BILTHOVEN NETHERLANDS NATL INST PUBL HLTH & ENVIRONM PROTECT,RIVM,PUBL HLTH RES DIV 3720 BABILTHOVEN NETHERLANDS UNIV MINNESOTA,SCH PUBL HLTH,DIV EPIDEMIOL MINNEAPOLIS MN 55455 UNIV KUOPIO,DEPT COMMUNITY HLTH & GEN PRACTICE SF-70211 KUOPIO FINLAND IST SUPER SANITA,EPIDEMIOL & BIOSTAT LAB I-00161 ROME ITALY NATL INST PUBL HLTH & ENVIRONM PROTECT,DEPT CHRON DIS & ENVIRONM EPIDEMIOL 3720 BA BILTHOVEN NETHERLANDS NATL PUBL HLTH INST SF-70211 KUOPIO FINLAND
Titolo Testata:
Preventive medicine
fascicolo: 3, volume: 25, anno: 1996,
pagine: 319 - 326
SICI:
0091-7435(1996)25:3<319:SAMAID>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; FACTOR INTERVENTION TRIAL; TOTAL SERUM-CHOLESTEROL; 25-YEAR FOLLOW-UP; BLOOD-PRESSURE; 7 COUNTRIES; BODY-WEIGHT; RISK; MEN; SURVIVAL;
Keywords:
ELDERLY; RISK FACTORS; MORTALITY; PREDICTION;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
27
Recensione:
Indirizzi per estratti:
Citazione:
A. Menotti et al., "SHORT-TERM ALL-CAUSE MORTALITY AND ITS DETERMINANTS IN ELDERLY MALE POPULATIONS IN FINLAND, THE NETHERLANDS, AND ITALY - THE FINE STUDY", Preventive medicine, 25(3), 1996, pp. 319-326

Abstract

Background. This study aims at identifying determinants of all-cause mortality in elderly populations of different countries. Methods. Men ages 65-84 years from defined administrative areas were enrolled in Finland (rural areas of east and west Finland; N = 693), in the Netherlands (the town of Zutphen; N = 851), and in Italy (the rural areas of Crevalcore and Montegiorgio; N = 682). They were survivors of cohorts studied for 25 years within the Seven Countries Study with the additionof a sub-group of the same ages in the Netherlands. Results. Five-year death rates from all causes were higher in Finland (297 per 1000), intermediate in the Netherlands (231 per 1000), and lower in Italy (191per 1000). Five-year all-cause mortality was studied in relation to measurements taken at entry (age, systolic and diastolic blood pressure, non-high-density lipo-protein (HDL) and HDL cholesterol, body mass index, heart rate, smoking habits, and presence of coronary heart disease manifestations). Univariate and multivariate analyses were performed (in the latter models, both linear and quadratic terms were used formost variables) with all-cause mortality as endpoint. Results suggested significant predictive power of age (direct relationship) and, in most cases, U-shaped relationships of risk factors to mortality. Non-HDL cholesterol showed significant relationships with mortality in Finland and the Netherlands, HDL cholesterol in all three countries, systolic blood pressure only in Finland, body mass index in Finland and the Netherlands, smoking habits only in Finland, and heart rate in none. Levels of risk factors associated with the lowest death rate in the pool of all countries were 183.3 mg/dl for non-HDL cholesterol, 59.8 for HDL cholesterol, 177.5 mm Hg for blood pressure, and 30.2 kg/m square for body mass index. Conclusions. In these elderly men the associationof traditional risk factors with all-cause mortality is reduced, U-shaped, or even inverted. This is probably due to selection due to previous mortality, to comorbidity, and to changes in homeostatic mechanisms. (C) 1996 Academic Press, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 06/04/20 alle ore 23:51:03