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OPAC HELP

Titolo:
TOXIC HEPATITIS - A RARE COMPLICATION ASSOCIATED WITH THE USE OF RITODRINE DURING PREGNANCY
Autore:
DEARCOS F; GRATACOS E; PALACIO M; CARARACH V;
Indirizzi:
UNIV BARCELONA,DEPT OBSTET & GINECOL,HOSP CLIN BARCELONA,VILLARROEL 170 E-08036 BARCELONA SPAIN
Titolo Testata:
Acta obstetricia et gynecologica Scandinavica
fascicolo: 4, volume: 75, anno: 1996,
pagine: 340 - 342
SICI:
0001-6349(1996)75:4<340:TH-ARC>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Keywords:
PREGNANCY; RITODRINE; SYMPATHOMIMETICS; TOXIC HEPATITIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
F. Dearcos et al., "TOXIC HEPATITIS - A RARE COMPLICATION ASSOCIATED WITH THE USE OF RITODRINE DURING PREGNANCY", Acta obstetricia et gynecologica Scandinavica, 75(4), 1996, pp. 340-342

Abstract

Objectives. To evaluate the incidence of toxic hepatitis associated with the use of ritodrine in pregnancy. Design. A prospective study. Setting. A large teaching hospital in Barcelona, Spain. Patients: One hundred and twenty-three consecutive pregnant women, 101 singleton and 22 multiple pregnancies, receiving intravenous ritodrine with normal transaminase levels prior to the initiation of therapy. Measurements. Serum glutamic pyruvic transaminase (SGPT) and glutamic oxaloacetic transaminase (SGOT), gamma-glutamyl transpeptidase (GGT), alkaline phosphatase (PA), direct and total bilirubin. Results. In two (1.9%) of 101 singleton and two (9.1%) of 22 multiple pregnancies, elevation of SGOT and SGPT levels was detected. PA, GGT, and bilirubin were normal in all women studied. Other causes of hepatitis were ruled out, and no other signs of liver impairment were found in these women. Transaminase levels recovered rapidly in all cases after discontinuation of therapy. Conclusion. Elevation of liver enzymes is a rare complication of ritodrine. Discontinuation of therapy does not appear to be indicated as long as other signs of liver dysfunction are not present and tocolytic treatment is required.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/02/20 alle ore 21:20:01