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Titolo:
RETINOPATHY OF PREMATURITY AND SURFACTANT TREATMENT
Autore:
AXERSIEGEL R; SNIR M; MAAYAN A; NAOR N; DAVIDSON S; WEINBERGER D; YASSUR Y;
Indirizzi:
BEILINSON MED CTR,DEPT OPHTHALMOL IL-49100 PETAH TIQWA ISRAEL
Titolo Testata:
Journal of pediatric ophthalmology and strabismus
fascicolo: 3, volume: 33, anno: 1996,
pagine: 171 - 174
SICI:
0191-3913(1996)33:3<171:ROPAST>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS SYNDROME; 30 WEEKS GESTATION; REPLACEMENT THERAPY; BOVINE SURFACTANT; RANDOMIZED TRIAL; CLINICAL-TRIAL; DOUBLE-BLIND; SYNTHETIC SURFACTANT; FINAL ANALYSIS; FOLLOW-UP;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
26
Recensione:
Indirizzi per estratti:
Citazione:
R. Axersiegel et al., "RETINOPATHY OF PREMATURITY AND SURFACTANT TREATMENT", Journal of pediatric ophthalmology and strabismus, 33(3), 1996, pp. 171-174

Abstract

Purpose: Surfactant therapy in premature infants has reduced the severity of respiratory distress syndrome (RDS), thus leading to a reduction in mortality. However, the anticipated effect of surfactant therapyon the incidence and severity of retinopathy of prematurity (ROP) is ambiguous. The acute rise in Pao(2) and the increased survival of low-birth-weight infants may augment the risk of ROP, whereas their improved health and respiratory status may lower it. Methods: We reviewed the findings of sequential ophthalmologic examinations performed in our neonatal intensive care unit. Premature infants of gestational age under 32 weeks and weighing less than 1500 g at birth who received surfactant treatment were compared with a group of historical controls consisting of premature infants of the same mean birth weight and gestational age who did not get this supplement. Results: ROP was present in 13(65%) of the 20 surfactant-treated babies, and threshold disease was noted in six (30%). In the historical control group, 20 (77%) of 25 infants had ROP, of whom 10 (40%) were treated for threshold disease. These differences were not statistically significant. Conclusion: Surfactant therapy was not associated with an increased incidence of ROP in our series.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 02:20:00