Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
NOVEL ACRYLAMIDO MONOMERS WITH HIGHER HYDROPHILICITY AND IMPROVED HYDROLYTIC STABILITY .2. PROPERTIES OF N-ACRYLOYLAMINOPROPANOL
Autore:
SIMOALFONSO E; GELFI C; SEBASTIANO R; CITTERIO A; RIGHETTI PG;
Indirizzi:
LITA,VIA FRATELLI CERVI 93 I-20090 SEGRATE MILANO ITALY UNIV VALENCIA,FAC QUIM,DEPT QUIM ANALIT E-46100 BURJASSOT SPAIN CNR,ITBA MILAN ITALY POLITECN MILAN,DEPT CHEM MILAN ITALY UNIV CALABRIA,DEPT CELL BIOL RENDE COSENZA ITALY
Titolo Testata:
Electrophoresis
fascicolo: 4, volume: 17, anno: 1996,
pagine: 732 - 737
SICI:
0173-0835(1996)17:4<732:NAMWHH>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Keywords:
N-SUBSTITUTED ACRYLAMIDES; N-ACRYLOYLAMINOPROPANOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
E. Simoalfonso et al., "NOVEL ACRYLAMIDO MONOMERS WITH HIGHER HYDROPHILICITY AND IMPROVED HYDROLYTIC STABILITY .2. PROPERTIES OF N-ACRYLOYLAMINOPROPANOL", Electrophoresis, 17(4), 1996, pp. 732-737

Abstract

The physico-chemical properties and the electrophoretic behavior of the novel set of monomers reported by (Simo-Alfonso et al., Electrophoresis 1996, 17, 723-731) have been evaluated. Of utmost importance was the combination of high hydrophilicity and extreme hydrolytic stability, most desired properties for any electrophoretic matrix, especially for protein fractionation. One of these monomers (N-acryloylaminopropanol, AAP) was found indeed to be extremely hydrophilic (with a partition coefficient P of only 0.10, vs. P = 0.13 for N-acryloylaminoethoxyethanol and P = 0.20 for acrylamide) and to possess excellent stabilityto alkaline hydrolysis. Its hydrolysis constant (0.008 L mol(-1) min(-1)), as a free monomer, in an alkaline milieu, was found to be about one order of magnitude lower than conventional acrylamide (0.05 L mol(-1) min(-1)). In the polymer state, the resistance to hydrolysis of poly(AAP) was assessed as 500 times greater than a conventional poly(acrylamide) matrix.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/12/20 alle ore 16:23:17