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Titolo:
INHIBITORY EFFECTS OF GREEN TEA POLYPHENOLS ON GROWTH AND CELLULAR ADHERENCE OF AN ORAL BACTERIUM, PORPHYROMONAS-GINGIVALIS
Autore:
SAKANAKA S; AIZAWA M; KIM M; YAMAMOTO T;
Indirizzi:
TAIYO KAGAKU CO LTD,CENT RES LABS,1-3 TAKARA MACHI YOKKAICHI MIE 510 JAPAN FUKUYAMA UNIV,DEPT BIOTECHNOL FUKUYAMA HIROSHIMA 72902 JAPAN
Titolo Testata:
Bioscience, biotechnology, and biochemistry
fascicolo: 5, volume: 60, anno: 1996,
pagine: 745 - 749
SICI:
0916-8451(1996)60:5<745:IEOGTP>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
BACTEROIDES-GINGIVALIS; STREPTOCOCCUS-MUTANS; EPITHELIAL-CELLS; ASACCHAROLYTICUS; FIMBRIAE;
Keywords:
GREEN TEA POLYPHENOLS; (-)-EPIGALLOCATECHIN GALLATE; PORPHYROMONAS GINGIVALIS; ADHERENCE; BUCCAL EPITHELIAL CELLS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
15
Recensione:
Indirizzi per estratti:
Citazione:
S. Sakanaka et al., "INHIBITORY EFFECTS OF GREEN TEA POLYPHENOLS ON GROWTH AND CELLULAR ADHERENCE OF AN ORAL BACTERIUM, PORPHYROMONAS-GINGIVALIS", Bioscience, biotechnology, and biochemistry, 60(5), 1996, pp. 745-749

Abstract

Effects of polyphenolic compounds isolated from green tea (Camellia sinensis) on the growth and adherence of Porphyromonas gingivalis onto human buccal epithelial cells were investigated, Green tea polyphenols, especially (-)-epigallocatechin gallate (EGCg) which is a dominant component of tea polyphenols, completely inhibited the growth and adherence of P. gingivalis onto the buccal epithelial cells at concentrations of 250-500 mu g/ml. Among the polyphenolic compounds, (-)-epicatechin gallate (ECg) and (-)-gallocatechin gallate (GCg) were effective next to EGCg in these activities, On the other hand, (+)-catechin (C-(+)), (-)-epicatechin (EC), (+)-gallocatechin (GC), and( -)-epigallocatechin (EGG) had very much less activity, These results indicate that theinhibitory effect on the adherence of P. gingivalis onto the buccal epithelial cells is attributed to the presence of the galloyl moiety, which is ester-linked with the 3-OH of the catechin moiety in the polyphenolic compounds.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/11/20 alle ore 16:12:44