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Titolo:
PREGNANCY OUTCOME AT AGE 40 AND OLDER
Autore:
BIANCO A; STONE J; LYNCH L; LAPINSKI R; BERKOWITZ G; BERKOWITZ RL;
Indirizzi:
NYU,MED CTR,DEPT OBSTET GYNECOL & REPROD SCI,550 1ST AVE,SKIRBALL SUITE 7V NEW YORK NY 10016 MT SINAI MED CTR,DEPT OBSTET GYNECOL & REPROD SCI NEW YORK NY 10029
Titolo Testata:
Obstetrics and gynecology
fascicolo: 6, volume: 87, anno: 1996,
pagine: 917 - 922
SICI:
0029-7844(1996)87:6<917:POAA4A>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADVANCED MATERNAL AGE; DELAYED CHILDBEARING; CESAREAN DELIVERY; PLACENTA-PREVIA; RISK FACTOR; ABNORMALITIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
30
Recensione:
Indirizzi per estratti:
Citazione:
A. Bianco et al., "PREGNANCY OUTCOME AT AGE 40 AND OLDER", Obstetrics and gynecology, 87(6), 1996, pp. 917-922

Abstract

Objective: To examine pregnancy outcome among women age 40 years and older. Methods: A retrospective cohort study, including 1404 pregnant women at least 40 years of age and 6978 controls age 20-29 years, was conducted. The two groups were stratified, according to parity, to facilitate separate analysis. Associations between maternal age and Pregnancy outcomes were assessed with the contingency chi(2) or two-tailed Fisher exact test. Multiple logistic regression was used to evaluate these associations and allowed for calculation of adjusted odds ratios (OR). Results: Older gravidas were more likely to develop gestational diabetes (nulliparas: OR 2.7, 95% confidence interval [CI] 1.9-3.7; multiparas: OR 3.8, 95% CI 2.7-5.4), preeclampsia (nulliparas: OR 1.8, 95% CI 1.3-2.6; multiparas: OR 1.9, 95% CI 1.2-2.9), and placenta previa (nulliparas: OR 13.0, 95% CI 4.8-35.0; multiparas: OR 6.4, 95% CI 2.6-15.6). Older women were also at increased risk for cesarean delivery(nulliparas: OR 3.1, 95% CI 2.6-3.7; multiparas: OR 3.3, 95% CI 2.6-4.1), operative vaginal delivery (nulliparas: OR 2.4, 95% CI 1.9-2.9; multiparas: OR 1.5, 95% CI 1.2-1.9), and induction of labor (nulliparas: OR 1.5, 95% CI 1.2-1.8; multiparas: OR 1.4, 95% CI 1.1-1.7). Older nulliparas had an increased incidence of abnormal labor patterns (OR 1.4, 95% CI 1.2-1.7), neonatal intensive care unit admissions (OR 1.6, 95% CI 1.2-2.2), and low 1-minute Apgar scores (OR 2.3, 95% CI 1.1-4.9). Older multiparas were more likely to experience fetal. distress (OR 2.0, 95% CI 1.4-2.8), antepartum vaginal bleeding (OR 1.8, 95% CI 1.1-3.1), and preterm premature rupture of membranes (OR 1.7, 95% CI 1.1-2.9). Conclusion: Although maternal morbidity was increased in the older gravidas, the overall neonatal outcome did not appear to be affected.

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Documento generato il 01/10/20 alle ore 07:01:42