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Titolo:
ISOLATION AND CHARACTERIZATION OF A HUMAN CDNA CLONE (GCN5L1) HOMOLOGOUS TO GCN5, A YEAST TRANSCRIPTION ACTIVATOR
Autore:
INOUE M; ISOMURA M; IKEGAWA S; FUJIWARA T; SHIN S; MORIYA H; NAKAMURA Y;
Indirizzi:
UNIV TOKYO,INST MED SCI,MOLEC MED LAB,MINATO KU,4-6-1 SHIROKANEDAI TOKYO 108 JAPAN UNIV TOKYO,INST MED SCI,MOLEC MED LAB,MINATO KU TOKYO 108 JAPAN CHIBA UNIV,SCH MED,DEPT ORTHOPED CHIBA 280 JAPAN OTSUKA PHARMACEUT CO LTD,OTSUKA GEN INST TOKUSHIMA JAPAN
Titolo Testata:
Cytogenetics and cell genetics
fascicolo: 1-2, volume: 73, anno: 1996,
pagine: 134 - 136
SICI:
0301-0171(1996)73:1-2<134:IACOAH>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
EXPRESSED SEQUENCE TAGS; HUMAN BRAIN; PROTEIN; IDENTIFICATION; SITE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
M. Inoue et al., "ISOLATION AND CHARACTERIZATION OF A HUMAN CDNA CLONE (GCN5L1) HOMOLOGOUS TO GCN5, A YEAST TRANSCRIPTION ACTIVATOR", Cytogenetics and cell genetics, 73(1-2), 1996, pp. 134-136

Abstract

We have isolated a novel human cDNA with a predicted amino acid sequence homologous to GCN5, a protein considered to be a regulator of transcriptional activation in yeast. This cDNA, termed GCN5L1 (GCN5-like 1), consists of 545 nucleotides including an open reading frame of 378 bp that encodes a 126-amino-acid peptide having 23.5% identity to yeast GCN5. Northern-blot analysis revealed transcription of this gene in all human tissues examined. We isolated a genomic clone corresponding to this cDNA from a human cosmid library and mapped it to chromosome 12q13-->q14 by fluorescent in situ hybridization (FISH).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 03:44:26