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Titolo:
MEASUREMENT OF LUNG-FUNCTION IN AWAKE 2-4-YEAR-OLD ASTHMATIC-CHILDRENDURING METHACHOLINE CHALLENGE AND ACUTE ASTHMA - A COMPARISON OF THE IMPULSE OSCILLATION TECHNIQUE, THE INTERRUPTER TECHNIQUE, AND TRANSCUTANEOUS MEASUREMENT OF OXYGEN VERSUS WHOLE-BODY PLETHYSMOGRAPHY
Autore:
KLUG B; BISGAARD H;
Indirizzi:
NATL UNIV HOSP,RIGSHOSP,DEPT PEDIAT 5003 DK-2100 COPENHAGEN DENMARK
Titolo Testata:
Pediatric pulmonology
fascicolo: 5, volume: 21, anno: 1996,
pagine: 290 - 300
SICI:
8755-6863(1996)21:5<290:MOLIA2>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
FORCED OSCILLATION; RESPIRATORY RESISTANCE; INHALED METHACHOLINE; AIRWAY-RESISTANCE; HISTAMINE; TENSION; RESPONSIVENESS; OSCILLOMETRY; PROVOCATION;
Keywords:
PRESCHOOL CHILDREN; ASTHMA; IMPULSE OSCILLATION TECHNIQUE; INTERRUPTER TECHNIQUE; WHOLE-BODY PLETHYSMOGRAPHY; TRANSCUTANEOUS MEASUREMENT OF OXYGEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
39
Recensione:
Indirizzi per estratti:
Citazione:
B. Klug e H. Bisgaard, "MEASUREMENT OF LUNG-FUNCTION IN AWAKE 2-4-YEAR-OLD ASTHMATIC-CHILDRENDURING METHACHOLINE CHALLENGE AND ACUTE ASTHMA - A COMPARISON OF THE IMPULSE OSCILLATION TECHNIQUE, THE INTERRUPTER TECHNIQUE, AND TRANSCUTANEOUS MEASUREMENT OF OXYGEN VERSUS WHOLE-BODY PLETHYSMOGRAPHY", Pediatric pulmonology, 21(5), 1996, pp. 290-300

Abstract

This study evaluated three techniques for testing of lung function inyoung awake children. We compared measurements by the forced or impulse oscillation technique (IOS), the interrupter technique (IT), and transcutaneous measurements of oxygen (tcPo(2)) with concomitant measurements of specific airway resistance (sRaw) during methacholine challenge in 20 stable asthmatic children, 2-4 years old. Measurements were performed with all techniques after each dose of methacholine and afterinhalation of a bronchodilator. Measurements were carried out during tidal breathing using a face-mask with a built-in mouthpiece. The ranking of sensitivity was as follows: sRaw > IOS, respiratory reactance at 5 Hz (Xrs5) > tcPo(2) > interrupter resistance (Rint) > IOS, respiratory resistance at 5 Hz (Rrs5). The sensitivity of sRaw and Xrs5 was not significantly different, but both were significantly more sensitivethan Rint and Rrs5; the sensitivity of tcPo(2), Rint, and Rrs5 was not significantly different. Measurements in eight of the subjects performed during an episode of acute asthma yielded comparable results in regard to the sensitivity of the techniques. Measurements improved significantly after bronchodilator administration; however, the response to bronchodilator tended to be less during acute asthma and was best demonstrated by a deterioration of tcPo(2). All the evaluated techniquesreliably reflect short-term changes in respiratory function and can provide clinically useful estimates of airway function. The techniques are non-invasive, are not dependent on the active co-operation or sedation of the subjects, and therefore are well suited for routine use inyoung children. (C) 1996 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 11:06:43