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Titolo:
CHOROID-PLEXUS - THE MAJOR SITE OF MESSENGER-RNA EXPRESSION FOR THE BETA-TRACE PROTEIN (PROSTAGLANDIN-D SYNTHASE) IN HUMAN BRAIN
Autore:
BLODORN B; MADER M; URADE Y; HAYAISHI O; FELGENHAUER K; BRUCK W;
Indirizzi:
UNIV GOTTINGEN,DEPT NEUROL,ROBERT KOCH STR 40 D-37075 GOTTINGEN GERMANY UNIV GOTTINGEN,DEPT NEUROL D-37075 GOTTINGEN GERMANY OSAKA BIOSCI INST SUITA OSAKA 565 JAPAN UNIV GOTTINGEN,DEPT NEUROPATHOL D-37075 GOTTINGEN GERMANY
Titolo Testata:
Neuroscience letters
fascicolo: 2, volume: 209, anno: 1996,
pagine: 117 - 120
SICI:
0304-3940(1996)209:2<117:C-TMSO>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN CEREBROSPINAL-FLUID; RAT-BRAIN; D SYNTHETASE; OLIGODENDROCYTES; PURIFICATION; SEQUENCE;
Keywords:
IN SITU HYBRIDIZATION; BETA-TRACE PROTEIN; PROSTAGLANDIN D SYNTHASE; CHOROID PLEXUS; OLIGODENDROCYTES; MENINGES; TESTIS; EPIDIDYMIS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
19
Recensione:
Indirizzi per estratti:
Citazione:
B. Blodorn et al., "CHOROID-PLEXUS - THE MAJOR SITE OF MESSENGER-RNA EXPRESSION FOR THE BETA-TRACE PROTEIN (PROSTAGLANDIN-D SYNTHASE) IN HUMAN BRAIN", Neuroscience letters, 209(2), 1996, pp. 117-120

Abstract

Expression of beta-trace protein (beta-trace), recently identified asglutathion-independent prostaglandin D synthase (prostaglandin-H-2 D-isomerase; EC 5.3.99.2), was localized in paraffin sections of the human brain by insitu hybridization using digoxigenin-labeled antisense cRNA probes. The mRNA for beta-trace was predominantly found in the epithelial cells of the choroid plexus. Hybridization signals were also obtained in some oligodendrocytes, particularly in the white matter. Inthe leptomeninges, specific signals were found in meningeal macrophages and in single cells of the arachnoid barrier layer. The cells exhibiting hybridization signals with the antisense cRNA probes for beta-trace were identified by counterstaining with antibodies directed against specific cell markers. Additionally, beta-trace mRNA was localized in tubular epithelial and basal cells of the human epididymis and in different cell types within the seminiferous epithelium of the testis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/06/20 alle ore 01:14:15