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Titolo:
ALCOHOLISM, HEPATITIS-B AND HEPATITIS-C VIRAL-INFECTIONS, AND IMPAIRED LIVER-FUNCTION AMONG TAIWANESE ABORIGINAL GROUPS
Autore:
SHEN CY; LEE HS; HUANG LC; TSAI KS; CHEN DS; CHENG ATA;
Indirizzi:
ACAD SINICA,INST BIOMED SCI TAIPEI 11529 TAIWAN ACAD SINICA,INST BIOMED SCI TAIPEI 11529 TAIWAN NATL TAIWAN UNIV HOSP,DEPT INTERNAL MED TAIPEI 100 TAIWAN BUDDHIST TZU CHI GEN HOSP,DEPT INTERNAL MED HUALIEN TAIWAN NATL TAIWAN UNIV HOSP,DEPT LAB MED TAIPEI TAIWAN
Titolo Testata:
American journal of epidemiology
fascicolo: 9, volume: 143, anno: 1996,
pagine: 936 - 942
SICI:
0002-9262(1996)143:9<936:AHAHVA>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
VIRUS-INFECTION; HEPATOCELLULAR-CARCINOMA; ANTIBODIES; DISEASE; PREVALENCE;
Keywords:
ALANINE AMINOTRANSFERASE; ALCOHOLISM; ASPARTATE AMINOTRANSFERASE; HEPATITIS B VIRUS; HEPATITIS C VIRUSES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
C.Y. Shen et al., "ALCOHOLISM, HEPATITIS-B AND HEPATITIS-C VIRAL-INFECTIONS, AND IMPAIRED LIVER-FUNCTION AMONG TAIWANESE ABORIGINAL GROUPS", American journal of epidemiology, 143(9), 1996, pp. 936-942

Abstract

Viral hepatitis and alcoholism prevail in four major Taiwanese aboriginal groups. To study the relative importance of the acquisition of hepatitis B virus or hepatitis C virus infection and alcoholism to the presence of impaired liver function in these groups, the authors conducted a semistructured clinical interview for alcoholism and test for seromarkers for viral hepatitis among 993 cohort members enrolled in 1990-1992 in an ongoing prospective study (Taiwan Aboriginal Study Project). The subjects' blood specimens were tested for serum alanine aminotransferase/aspartate aminotransferase levels and for the presence of hepatitis B surface antigen and anti-hepatitis C virus antibody. The prevalence of a combination of an alanine aminotransferase level of >35 IU/liter and an aspartate aminotransferase level of >40 IU/liter, implying impaired liver function or advanced liver disease, was 4.3% overall. Univariate and multiple logistic regression analysis showed that, rather than chronic hepatitis B virus infection, hepatitis C virus infection and alcoholism were the two dominant risk factors that signalled the risk of liver damage among these Taiwanese aborigines. In addition, these two contributing factors were able to act synergistically tocause impaired liver function.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 05:23:27