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Titolo:
MAGNETIC-RESONANCE-IMAGING OF THE BRAIN-BLOOD PARTITION-COEFFICIENT FOR WATER - APPLICATION TO SPIN-TAGGING MEASUREMENT OF PERFUSION
Autore:
ROBERTS DA; RIZI R; LENKINSKI RE; LEIGH JS;
Indirizzi:
UNIV PENN,MED CTR,DEPT RADIOL PHILADELPHIA PA 19104
Titolo Testata:
Journal of magnetic resonance imaging
fascicolo: 2, volume: 6, anno: 1996,
pagine: 363 - 366
SICI:
1053-1807(1996)6:2<363:MOTBPF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERIAL WATER; PROTON DENSITY; RELAXATION; INVERSION; VOLUME;
Keywords:
MRI; PERFUSION IMAGING; PARTITION COEFFICIENT; SPIN-TAGGING; FUNCTIONAL IMAGING;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
D.A. Roberts et al., "MAGNETIC-RESONANCE-IMAGING OF THE BRAIN-BLOOD PARTITION-COEFFICIENT FOR WATER - APPLICATION TO SPIN-TAGGING MEASUREMENT OF PERFUSION", Journal of magnetic resonance imaging, 6(2), 1996, pp. 363-366

Abstract

We describe the use of relative proton density imaging to obtain spatially resolved measurements of the brain:blood partition coefficient for water, Values of. relative proton density and apparent-T1 were calculated by performing a multidimensional nonlinear least squares fit ofprogressive saturation image data, Correction for magnetic field inhomogeneity was included. The partition coefficient was calculated by dividing the relative proton density of brain by the relative proton density of blood water, Results obtained from healthy volunteers demonstrate significant spatial variation in the partition coefficient in brain. Direct measurement of this parameter eliminates a source of error in the calculation of regional perfusion using arterial spin-tagging techniques.

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Documento generato il 30/10/20 alle ore 09:43:39