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Titolo:
SILICA AND ALUMINUM IN DRINKING-WATER AND COGNITIVE IMPAIRMENT IN THEELDERLY
Autore:
JACQMINGADDA H; COMMENGES D; LETENNEUR L; DARTIGUES JF;
Indirizzi:
INSERM U330,146 RUE LEO SAIGNAT F-33076 BORDEAUX FRANCE
Titolo Testata:
Epidemiology
fascicolo: 3, volume: 7, anno: 1996,
pagine: 281 - 285
SICI:
1044-3983(1996)7:3<281:SAAIDA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; DEMENTIA; PAQUID;
Keywords:
ALUMINUM; ALZHEIMERS DISEASE; COGNITIVE IMPAIRMENT; DEMENTIA; DRINKING WATER; ELDERLY; SILICON;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
H. Jacqmingadda et al., "SILICA AND ALUMINUM IN DRINKING-WATER AND COGNITIVE IMPAIRMENT IN THEELDERLY", Epidemiology, 7(3), 1996, pp. 281-285

Abstract

We studied the relation between silica and aluminum levels in drinking water and the risk of cognitive impairment using data from a population-based survey of 3,777 French subjects age 65 years and older. We also studied the effect of pH and the concentrations of calcium, magnesium, fluorine, zinc, copper, and iron. We used a mixed effects logistic regression adjusting for age, sex, educational level, and occupationof the subjects. We confirmed the inverse relation previously found between calcium level and cognitive impairment. We found no important association between cognitive impairment and fluorine, magnesium, iron,copper, or:inc. The association between cognitive impairment and aluminum depended on the pH and the concentration of silica: high levels of aluminum appeared to have a deleterious effect when the silica concentration was low, but there was a protective effect when the pH and the silica level were high. The threshold for an aluminum effect, however, was very low (3.5 mu g per liter) and did not support the hypothesis of a deleterious effect for only high levels of aluminum.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 21:56:59