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Titolo:
SLEEP-EPILEPSY INTERACTIONS IN PATIENTS WITH INTRACTABLE GENERALIZED TONIC SEIZURES AND DEPTH ELECTRODES IN THE CENTROMEDIAN THALAMIC NUCLEUS
Autore:
VELASCO M; DIAZDELEON AE; BRITO F; VELASCO AL; VELASCO F;
Indirizzi:
CTR MED NACL SIGLO 21,UMR NEUROPHYSIOL,APTDO POSTAL 73-032 MEXICO CITY DF MEXICO SSA,GEN HOSP,UNIDAD NEUROL MEXICO CITY DF MEXICO SSA,GEN HOSP,UNIDAD NEUROCIRUGIA MEXICO CITY DF MEXICO SSA,HOSP PEDIAT MEXICO CITY DF MEXICO INST MEXICANO SEGURO SOCIAL,CTR MED NACL SIGLO 21,UNIDAD INVEST MED NEUROFIS MEXICO CITY DF MEXICO
Titolo Testata:
Archives of medical research
, volume: 26, anno: 1995,
pagine: 117 - 125
SICI:
0188-4409(1995)26:<117:SIIPWI>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
LENNOX-GASTAUT SYNDROME; PARTIALIS CONTINUA; EVOKED-POTENTIALS; INFANTILE SPASMS; EEG; MODULATION; CHILDREN;
Keywords:
GENERALIZED TONIC SEIZURES; LENNOX-GASTAUT SYNDROME; CM THALAMIC NUCLEUS; EFFECT OF EPILEPSY ON SLEEP; EFFECT OF SLEEP ON EPILEPSY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
M. Velasco et al., "SLEEP-EPILEPSY INTERACTIONS IN PATIENTS WITH INTRACTABLE GENERALIZED TONIC SEIZURES AND DEPTH ELECTRODES IN THE CENTROMEDIAN THALAMIC NUCLEUS", Archives of medical research, 26, 1995, pp. 117-125

Abstract

Sleep-epilepsy interactions were studied in ten patients with Lennox-Gastaut Syndrome (LSG) suffering intractable generalized tonic seizures associated with generalized ictal fast spikes and interictal slow spike-wave complexes, where electrodes were implanted in the centromedian thalamic nucleus (CM) as part of a neuroaugmentive procedure for seizure control. In these patients, continuous all night recordings according to International Guidelines were performed to quantitatively determine changes in sleep patterns produced by the epileptic condition and changes in ictal and interictal surface and CM EEG activities produced by sleep stages, LGS patients showed significantly longer wakefulness (W) and shorter slow wave sleep (SWS) II than normals. Patients with seizures during the night showed shorter latency and larger number of paradoxical sleep (PS) periods than those patients without seizures. Ictal and interictal spike-wave EEG activities appeared together in surface and CM regions during all sleep stages with a ratio SURFACE/CM almost equal to one and PS did not focalize ictal and interictal activities in thalamic or cortical regions. Occurrence and duration of ''myoclonic'' ictal EEG component and number of interictal spike-wave complexes were higher during SWS II while they were smaller during PS thanduring W.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 18:25:53