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Titolo:
A RANDOMIZED COMPARISON OF A BIPOLAR STEROID-ELUTING ELECTRODE AND A BIPOLAR MICROPOROUS PLATINUM-ELECTRODE - IMPLICATIONS FOR LONG-TERM PROGRAMMING
Autore:
GILLIS AM; ROTHSCHILD JM; HILLIER K; FUDGE W; KIESER TM; MAITLAND A;
Indirizzi:
UNIV CALGARY,DEPT MED,DIV CARDIOL,3330 HOSP DR NW CALGARY T2N 4N1 AB CANADA UNIV CALGARY,DIV CARDIOVASC SURG CALGARY T2N 4N1 AB CANADA FOOTHILLS PROV GEN HOSP,MED CTR CALGARY AB CANADA
Titolo Testata:
PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY
fascicolo: 5, volume: 16, anno: 1993,
parte:, 1
pagine: 964 - 970
SICI:
0147-8389(1993)16:5<964:ARCOAB>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
PACEMAKER LEADS; PERFORMANCE;
Keywords:
STEROID-ELUTING LEADS; MICROPOROUS LEADS; PACING THRESHOLDS; PROGRAMMING PULSE GENERATORS;
Tipo documento:
Article
Natura:
Periodico
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
A.M. Gillis et al., "A RANDOMIZED COMPARISON OF A BIPOLAR STEROID-ELUTING ELECTRODE AND A BIPOLAR MICROPOROUS PLATINUM-ELECTRODE - IMPLICATIONS FOR LONG-TERM PROGRAMMING", PACE, 16(5), 1993, pp. 964-970

Abstract

Differences in acute and chronic pacing thresholds were compared in patients receiving either the Medtronic Model 4004 steroid-eluting leador the Medtronic Model 4012 microporous platinum lead. Patients (n = 35) were randomized at the time of implant to receive either a steroid-eluting (n = 17) or a microporous (n = 18) lead. Pacing thresholds were determined within 24 hours and at 2, 4, 6, 12, 24, and 52 weeks postimplant. By 2 weeks postimplant, pacing thresholds measured at 0.8, 1.6, 2.5, 3.3, and 4.2 V were significantly lower in the steroid lead group compared to the microporous lead group (P < 0.05). At 24 weeks, the voltage threshold at 0.3 msec was 0.8 V in 88% of patients with a steroid lead whereas this threshold was only observed in 33% of patients with the microporous lead (P < 0.01). At 52 weeks the pacing energy measured at 1.6 V, twice pulse duration threshold, was significantly lower in the steroid lead group (0.81 +/- 0.59 muJ) compared to the microporous lead group (1.25 +/- 0.60 muJ, P < 0.05). Thirteen patients in the steroid lead group and 9 patients in the microporous lead group have been programmed at a pulse amplitude of 1.6 V since the 24-week follow-up visit. These patients have been followed for a minimum of 6 months without documented failure to capture. This study shows that pacemaker/lead systems with stable chronic low thresholds can be safely programmed to low pulse amplitude settings. This practice will prolong the longevity of pulse generators.

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Documento generato il 22/09/20 alle ore 10:03:31