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Titolo:
AMBULATORY BLOOD-PRESSURE MONITORING FOR EVALUATION OF LONG-ACTING BETA-BLOCKERS IN TAIWAN
Autore:
TSENG CD; TSENG YZ; LO HM; CHIANG FT; HSU KL;
Indirizzi:
NATL TAIWAN UNIV HOSP,DEPT INTERNAL MED,7 CHUNG SHAN S RD TAIPEI 100 TAIWAN
Titolo Testata:
Journal of the Formosan Medical Association
fascicolo: 4, volume: 95, anno: 1996,
pagine: 320 - 324
SICI:
0929-6646(1996)95:4<320:ABMFEO>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
HYPERTENSIVE PATIENTS; ATENOLOL; PROPRANOLOL; METOPROLOL; MORTALITY;
Keywords:
HYPERTENSION; AMBULATORY BLOOD PRESSURE MONITORING; METOPROLOL; ATENOLOL; NADOLOL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
35
Recensione:
Indirizzi per estratti:
Citazione:
C.D. Tseng et al., "AMBULATORY BLOOD-PRESSURE MONITORING FOR EVALUATION OF LONG-ACTING BETA-BLOCKERS IN TAIWAN", Journal of the Formosan Medical Association, 95(4), 1996, pp. 320-324

Abstract

This study attempted to evaluate the efficacy of several ''long-acting'' antihypertensive agents. One-hundred consecutive hypertensive subjects with normal casual blood pressure after once-daily antihypertensive monotherapy treatment were studied. They were divided into three groups: group A, metoprolol (100 mg, daily; group B, atenolol (100 mg, daily); and group C, nadolol (80 mg, daily). Ambulatory blood pressure monitoring (ABPM) was used to evaluate the efficacy of the antihypertensive agents. The overall average ambulatory blood pressures were within the normal limits for all thr ee groups. However, there were some abnormally high blood pressure (BP) readings shown on ABPM. Patients with tin abnormally high systolic blood pressure (SEP) average > 140 mmHg: accounted for 16.7% of group Al 19.4% of group B and 20% of group C. Those with an abnormally high diastolic blood pressure (DBP) average> 90 mmHg accounted for 16.7%, 19.4% and 10%, respectively, of the corresponding groups. There were no significant differences in the frequency of abnormally high SEP and DBP among the three groups. These ''long-acting'' antihypertensive drugs did not effectively control BP throughout the entire day. The duration of antihypertensive effect is not necessarily reflected by the blood half-life of the drug. ABPM is an effective way to ascertain the efficacy of ''long-acting'' hypertensiveagents.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 13:48:44