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Titolo:
THE EFFECT OF ETHANOL AND CALCIUM-CHANNEL ANTAGONISTS ON RABBIT EEG
Autore:
CZARNECKA E; PIETRZAK B;
Indirizzi:
MED UNIV LODZ,DEPT PHARMACOL,MUSZYNSKIEGO 1 PL-90151 LODZ POLAND
Titolo Testata:
Alcohol
fascicolo: 3, volume: 13, anno: 1996,
pagine: 221 - 226
SICI:
0741-8329(1996)13:3<221:TEOEAC>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTRY BLOCKERS; VERAPAMIL; BINDING; BRAIN; RAT; NICARDIPINE; NIFEDIPINE; DILTIAZEM; DRINKING; SITES;
Keywords:
EEG; ETHANOL; NIFEDIPINE; CINNARIZINE; VERAPAMIL;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
41
Recensione:
Indirizzi per estratti:
Citazione:
E. Czarnecka e B. Pietrzak, "THE EFFECT OF ETHANOL AND CALCIUM-CHANNEL ANTAGONISTS ON RABBIT EEG", Alcohol, 13(3), 1996, pp. 221-226

Abstract

The influence of nifedipine, verapamil, and cinnarizine on the effectof ethanol on EEG of rabbits (frontal cortex, hippocampus, MRF) was tested. Nifedipine (1.75 mg/kg, IP) and cinnarizine (7.5 mg/kg, IP) were given 30 min before ethanol administration. Verapamil (0.2 mg/kg, IV) was given 15 min before ethanol injection in a dose of 0.8 g/kg IV. Ethanol caused the increase of the frequencies 0.5-4 cps in the recording, as well as a marked decrease of the fastest frequencies. Verapamil prevented ethanol's effect on EEG recording. Cinnarizine antagonizedthis action to a smaller extent and the influence of nifedipine is transitory and less pronounced.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 14/11/18 alle ore 04:18:36