Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
EARLY CLINICAL-EXPERIENCE WITH PREOPERATI VE MR-GUIDED LASER-INDUCED THERMOTHERAPY (LITT) OF LIVER METASTASES
Autore:
VOGL TJ; WEINHOLD N; MULLER P; PHILLIP C; ROGGAN A; MACK MG; BALZER JO; EICHSTADT H; BLUMHARDT G; LOBECK H; FELIX R;
Indirizzi:
HUMBOLDT UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,FAK MED,STRAHLENKLIN & POLIKLIN,AUGUSTENBURGER PL 1 D-13353 BERLIN GERMANY LASER & MED TECHNOL GGMBH BERLIN GERMANY HUMBOLDT UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,CHIRURG KLIN & POLIKLIN D-13353 BERLIN GERMANY HUMBOLDT UNIV BERLIN,KLINIKUM RUDOLF VIRCHOW,INST PATHOL D-13353 BERLIN GERMANY
Titolo Testata:
RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren
fascicolo: 5, volume: 164, anno: 1996,
pagine: 413 - 421
SICI:
0936-6652(1996)164:5<413:ECWPVM>2.0.ZU;2-4
Fonte:
ISI
Lingua:
GER
Soggetto:
YAG LASER; HYPERTHERMIA; PHOTOCOAGULATION; IRRADIATION; NEODYMIUM; TISSUE; MODEL;
Keywords:
LASERS, INTERSTITIAL THERMOTHERAPY; LIVER, INTERVENTIONAL PROCEDURE; LIVER NEOPLASMS, METASTASES; LIVER NEOPLASMS, THERAPY; MAGNETIC RESONANCE (MR), THERMOMETRY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
20
Recensione:
Indirizzi per estratti:
Citazione:
T.J. Vogl et al., "EARLY CLINICAL-EXPERIENCE WITH PREOPERATI VE MR-GUIDED LASER-INDUCED THERMOTHERAPY (LITT) OF LIVER METASTASES", RoFo. Fortschritte auf dem Gebiete der Rontgenstrahlen und der neuenbildgebenden Verfahren, 164(5), 1996, pp. 413-421

Abstract

Purpose: To evaluate the LITT-induced changes with the aid of MRT andcorrelate these with histopathological findings. Material and methods: Five patients with solitary cole rectal liver metastases were treated by means of MR-guided LITT before liver resection. Application time and energy of the Nd:YAG laser (1064 nm) was 10-20 minutes and 4.5-8.8W. MRT monitoring during the LITT was carried out with temperature-sensitive T-1 weighted sequences (FLASH-2-D, turbo FLASH). The extent ofthe induced necrosis as seen on MR was compared with the unfixed specimen and with the histopathological findings. Results: The extent of necrosis visible by MRT correlated with the histopathological findings with an accuracy of 95.3%+/-4.2 %. Following single treatments (three cases) the metastases suffered a reduction of 24%-55 % of their original volume. In two patients a second application produced laser-inducednecrosis of 78 % and 98 % of volume. In these two patients a temperature sound was used for measuring regional healing and showed an exact correlation with MR thermometry. Conclusion: The results of pre-operative MR-guided LITT indicates the potential of this form of treatment for obtaining reproducible tumor necrosis of liver metastases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/12/20 alle ore 01:42:39