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Titolo:
POSTMORTEM EXAMINATION OF GLIOBLASTOMA-MULTIFORME IN WHOLE BRAIN SECTIONS
Autore:
MENNEL HD; BINGENER J;
Indirizzi:
UNIV MARBURG,KLINIKUM LAHNBERGE,PATHOL MED CTR,DEPT NEUROPATHOL,BALDINGERSTR 1 W-3550 MARBURG GERMANY
Titolo Testata:
Tumordiagnostik & Therapie
fascicolo: 2, volume: 14, anno: 1993,
pagine: 66 - 71
SICI:
0722-219X(1993)14:2<66:PEOGIW>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
UNTREATED GLIOBLASTOMA; CYTOLOGIC COMPOSITION;
Keywords:
GLIOBLASTOMAS; POSTMORTEM INVESTIGATION; DOUBLE HEMISPHERIC PREPARATION; MORPHOMETRY; CT ANALOGIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
17
Recensione:
Indirizzi per estratti:
Citazione:
H.D. Mennel e J. Bingener, "POSTMORTEM EXAMINATION OF GLIOBLASTOMA-MULTIFORME IN WHOLE BRAIN SECTIONS", Tumordiagnostik & Therapie, 14(2), 1993, pp. 66-71

Abstract

Twelve glioblastomas were investigated in postmortem double hemispheric preparations by morphology and morphometry. Five of them were recurrent tumors after previous treatment. Three areas, or compartments, could be distinguished: a necrotic zone, a cellular proliferation zone, and the adjacent brain. Necroses in recurrent tumors had a higher relative share. Measurements and counting of vessels showed an increase from the periphery to the necrotic center, where they were not functionally active. Counting and distribution analysis of cell types showed the heterogeneity so typical of glioblastoma. On the other hand, recurrent tumors had slightly different distributions of cell size and shape. There is good correlation to findings of compartmental areas in the CT, but the latter gives a more general and simplified overall picture of the histological architecture.

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Documento generato il 23/09/20 alle ore 09:40:37