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Titolo:
ASSESSING CORONARY FLOW PHYSIOLOGY WITH INTRACORONARY DOPPLER FOLLOWING CORONARY INTERVENTIONS
Autore:
HIGANO ST; LERMAN A; GARRATT KN; NISHIMURA RA; HOLMES DR;
Indirizzi:
MAYO CLIN & MAYO FDN,DIV CARDIOVASC DIS & INTERNAL MED,200 1ST ST SW ROCHESTER MN 55902
Titolo Testata:
Journal of interventional cardiology
fascicolo: 2, volume: 9, anno: 1996,
pagine: 163 - 173
SICI:
0896-4327(1996)9:2<163:ACFPWI>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
INSTANTANEOUS HYPEREMIC FLOW; PRESSURE SLOPE INDEX; BLOOD-FLOW; STENOSIS SEVERITY; CONTINUITY EQUATION; GUIDE-WIRE; RESERVE MEASUREMENTS; VELOCITY DYNAMICS; ANGIOPLASTY; ARTERY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
56
Recensione:
Indirizzi per estratti:
Citazione:
S.T. Higano et al., "ASSESSING CORONARY FLOW PHYSIOLOGY WITH INTRACORONARY DOPPLER FOLLOWING CORONARY INTERVENTIONS", Journal of interventional cardiology, 9(2), 1996, pp. 163-173

Abstract

Although coronary angiography has been the gold standard for assessing coronary artery stenoses, it yields information primarily about the anatomical severity of coronary artery disease, which frequently does not correlate with its physiological severity. Coronary interventions (PTCA, atherectomy, laser, etc.) are performed primarily to improve coronary flow physiology. Coronary flow physiology may be a more important end point than angiography following coronary interventions that were performed to normalize coronary flow physiology. in addition, the physiological significance of angiographically intermediate stenoses should be assessed before proceeding with catheter-based revascularization. Currently, the Doppler guidewire is available for routine clinicalassessment of coronary flow physiology in the Cardiac CatheterizationLab. Several Doppler measurements have been used to assess the physiological effect of a stenosis, including the diastolic-systolic velocity ratio, proximal-distal velocity ratio, coronary flow reserve, continuity equation, and the hyperemic diastolic pressure-flow relationship. The Doppler derived coronary flow reserve correlates highly with stress nuclear perfusion images. These Doppler measurements have been madefollowing PTCA, directional atherectomy, rotational atherectomy, and excimer laser. Following coronary interventions, adverse clinical events may be predicted if there is impaired flow physiology or cyclic flow variations. Many of the Doppler measurements used for assessing the lesion severity remain abnormal following successful coronary interventions for reasons unrelated to the lesion. Conversely, normalization of coronary physiology does not guarantee an adequate anatomical result. Further clinical trials will provide a more complete definition of the exact role for coronary flow velocity assessment following coronaryinterventions.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 17:05:51