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Titolo:
CONSISTENCY TESTING OF TOPICALLY APPLIED SYSTEMS BY PENETRATION MEASUREMENTS
Autore:
BECK G; NURNBERG E;
Indirizzi:
INST PHARM TECHNOL,CAUERSTR 4 D-91058 ERLANGEN GERMANY UNIV ERLANGEN NURNBERG,LEHRSTUHL PHARMAZEUT TECHNOL W-8520 ERLANGEN GERMANY
Titolo Testata:
Die Pharmazie
fascicolo: 5, volume: 51, anno: 1996,
pagine: 297 - 303
SICI:
0031-7144(1996)51:5<297:CTOTAS>2.0.ZU;2-C
Fonte:
ISI
Lingua:
GER
Soggetto:
OIL NUMBER; PETROLATUM;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
6
Recensione:
Indirizzi per estratti:
Citazione:
G. Beck e E. Nurnberg, "CONSISTENCY TESTING OF TOPICALLY APPLIED SYSTEMS BY PENETRATION MEASUREMENTS", Die Pharmazie, 51(5), 1996, pp. 297-303

Abstract

The third Supplement to the German pharmacopoeia DAB 10 contained a test method for the consistency of topically applied systems using penetration. Measurements of penetration showed clear differences between various ointments, cremes and gels. The results obtained depend greatly on the method used. Method A of DAB 10 proved to be advantageous andreproducible. The DAB contains two apparatuses of different size, as well as various methods for preparing the samples. The macropenetration method shows more clearly differences in consistency, whereas the micropenetration is more relevant for practice. The latter uses only 5 gof sample, whereas the former requires relatively large amounts of 150 g. The two methods give quite different results. The penetration test according to DAB 10 is suitable for the development of ointment, creme and gelbasis as well as for quality control. Various aspects have, however, to be born in mind; they are discussed in this article.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 11:50:47