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Titolo:
PRODUCTION OF TYPE-I INTERFERONS UNDER TH E EFFECT OF YEAST RNA-TILORON MOLECULAR-COMPLEXES
Autore:
KARPOV AV; ZHOLOBAK NM;
Indirizzi:
DK ZABOLOTNYI MICROBIOL & VIROL INST KIEV UKRAINE
Titolo Testata:
Voprosy virusologii
fascicolo: 1, volume: 41, anno: 1996,
pagine: 13 - 16
SICI:
0507-4088(1996)41:1<13:POTIUT>2.0.ZU;2-R
Fonte:
ISI
Lingua:
RUS
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
9
Recensione:
Indirizzi per estratti:
Citazione:
A.V. Karpov e N.M. Zholobak, "PRODUCTION OF TYPE-I INTERFERONS UNDER TH E EFFECT OF YEAST RNA-TILORON MOLECULAR-COMPLEXES", Voprosy virusologii, 41(1), 1996, pp. 13-16

Abstract

Molecular complexes forming as a result of interaction between yeast RNA preparations with 2,7-bis[-(diethylaminoethoxy)-fluorene]-9-on dihidrochloride (tiloron) administered parenterally to mice cause the appearance of interferon in high titers compatible to those induced by standard inductors of polyribonucleotide origin, poly(I)-poly(C) and larifan. Some physiologic conditions of interferonogenesis have been studied. The above molecular complexes in the dose range used experimentally were completely nontoxic. Hence, these complexes are promising agents for interferon induction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/09/20 alle ore 12:10:54