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Titolo:
CHANGES OF PLASMA ATRIAL AND BRAIN NATRIURETIC PEPTIDE LEVELS DURING HEMODIALYSIS
Autore:
ISHIKURA F; ANDO Y; PARK YD; TANI A; SHIRAI D; MATSUOKA H; MIYATAKE K;
Indirizzi:
OSAKA POLICE HOSP,DEPT CARDIOL,TENNOUJI KU,10-31 KITAYAMA CHOU OSAKA 543 JAPAN OSAKA KOSEINENKIN HOSP,DEPT MED,DIV CARDIOL OSAKA 535 JAPAN
Titolo Testata:
Renal failure
fascicolo: 2, volume: 18, anno: 1996,
pagine: 261 - 270
SICI:
0886-022X(1996)18:2<261:COPAAB>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHRONIC-RENAL-FAILURE; CONGESTIVE-HEART-FAILURE; ECHOCARDIOGRAPHIC MEASUREMENTS; MITRAL-STENOSIS; CARDIAC HORMONE; SECRETION; SEQUENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
F. Ishikura et al., "CHANGES OF PLASMA ATRIAL AND BRAIN NATRIURETIC PEPTIDE LEVELS DURING HEMODIALYSIS", Renal failure, 18(2), 1996, pp. 261-270

Abstract

Objectives. The purpose of this study was to evaluate the effect of hemodialysis on the plasma concentration of atrial and brain natriuretic peptides, and to determine the two-dimensional echocardiographic parameters affecting the changes of plasma atrial and brain natriuretic peptide levels in patients with chronic renal failure. Background. Brain natriuretic peptide has been found in human cardiac tissue and increases in patients with congestive heart failure. However the factors that stimulate the secretion of plasma brain natriuretic peptide have not yet been fully clarified. Methods. In 15 patients with chronic renalfailure, plasma atrial and brain natriuretic peptide levels and two-dimensional echocardiographic parameters were measured before and aftereach session of hemodialysis. Results. Plasma atrial natriuretic peptide levels significantly decreased from 367 +/- 537 pg/mL to 138 +/- 167 pg/mL after hemodialysis (p < 0.01). However plasma brain natriuretic peptide levels did not significantly change after hemodialysis. Left atrial dimension signlficantly decreased (41.1 +/- 6.6 vs. 36.3 +/- 6.2 mm, p < 0.01) and left ventricular end-diastolic dimension slightly decreased after hemodialysis (57.0 +/- 10.3 vs. 55.7 +/- 9.9 mm, p <0.05). The decrease of left atrial dimension was greater than that ofleft ventricular end-diastolic dimension (4.9 +/- 1.6 vs. 1.3 +/- 0.6mm, p < 0.05). Plasma brain natriuretic peptide levels significantly correlated with fractional shortening both before and after hemodialysis (r = 0.65, p < 0.05). Conclusion. Plasma atrial natriuretic peptidelevels significantly decreased as the right and left atrial overloadsdecreased, and plasma brain natriuretic peptide levels did not significantly decrease after hemodialysis. Plasma brain natriuretic peptide levels were not significantly influenced by acute hemodynamic change, such as hemodialysis. However plasma brain natriuretic peptide levels were significantly correlated with basic cardiac function.

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Documento generato il 28/09/20 alle ore 18:39:19