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Titolo:
FUTURE-PROSPECTS FOR ALZHEIMERS-DISEASE THERAPY - ETHICAL AND POLICY ISSUES FOR THE INTERNATIONAL COMMUNITY
Autore:
WHITEHOUSE PJ;
Indirizzi:
CASE WESTERN RESERVE UNIV,UNIV HOSP CLEVELAND,ALZHEIMER CTR,2074 ABINGTON RD CLEVELAND OH 44106
Titolo Testata:
Acta neurologica Scandinavica
, volume: 93, anno: 1996, supplemento:, 165
pagine: 145 - 149
SICI:
0001-6314(1996)93:<145:FFAT-E>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Keywords:
ALZHEIMERS DISEASE; COMMUNITY; DRUG DEVELOPMENT; ETHICS; PHARMACOECONOMICS; POLICY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
P.J. Whitehouse, "FUTURE-PROSPECTS FOR ALZHEIMERS-DISEASE THERAPY - ETHICAL AND POLICY ISSUES FOR THE INTERNATIONAL COMMUNITY", Acta neurologica Scandinavica, 93, 1996, pp. 145-149

Abstract

In addition to being driven by basic scientific research and the preclinical and clinical evaluation of promising new compounds, the development of drugs for patients with Alzheimer's disease (AD) must also beguided by public policy and ethical considerations. More carefully coordinated efforts should be devoted to reducing caregiver burden and providing community-based health care services for patients with chronic as opposed to acute diseases. Important ethical issues include the appropriate duration of double-blind, placebo-controlled clinical trials, the determination of the meaning of ''informed consent'' when dealing with patients with dementia, the establishment of outcome goals forvarious stages of the disease process, and the provision of appropriate hospice-type care. The establishment of the International Working Group on Harmonization of Dementia Drug Guidelines is an important stepin the process of achieving an international approach toward the development and evaluation of drugs for patients with AD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/10/20 alle ore 14:43:27