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Titolo:
BRAIN-STEM TRIGEMINAL AND AUDITORY-EVOKED POTENTIALS IN MULTIPLE-SCLEROSIS - PHYSIOLOGICAL INSIGHTS
Autore:
SOUSTIEL JF; HAFNER H; CHISTYAKOV AV; YARNITZKY D; SHARF B; GUILBURD JN; FEINSOD M;
Indirizzi:
TECHNION ISRAEL INST TECHNOL,FAC MED,RAMBAM MED CTR,DEPT NEUROSURG,POB 9602 IL-31096 HAIFA ISRAEL TECHNION ISRAEL INST TECHNOL,FAC MED,RAMBAM MED CTR,DEPT NEUROL IL-31096 HAIFA ISRAEL TECHNION ISRAEL INST TECHNOL,FAC MED,BNEI ZION MED CTR,DEPT NEUROL IL-31096 HAIFA ISRAEL
Titolo Testata:
Electroencephalography and clinical neurophysiology. Evoked potentials
fascicolo: 2, volume: 100, anno: 1996,
pagine: 152 - 157
SICI:
0168-5597(1996)100:2<152:BTAAPI>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
INFRAORBITAL NERVE-STIMULATION; RESPONSES; ABNORMALITIES; NEURALGIA; LATENCY; ORIGIN; JAW;
Keywords:
MULTIPLE SCLEROSIS; BRAIN-STEM AUDITORY EVOKED POTENTIAL; BRAIN-STEM TRIGEMINAL EVOKED POTENTIAL; TRIGEMINAL NEURALGIA; MRI;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
33
Recensione:
Indirizzi per estratti:
Citazione:
J.F. Soustiel et al., "BRAIN-STEM TRIGEMINAL AND AUDITORY-EVOKED POTENTIALS IN MULTIPLE-SCLEROSIS - PHYSIOLOGICAL INSIGHTS", Electroencephalography and clinical neurophysiology. Evoked potentials, 100(2), 1996, pp. 152-157

Abstract

Thirty-six patients with multiple sclerosis were evaluated by means of brain-stem trigeminal and auditory evoked potentials. The brain-stemauditory evoked potentials (BAEPs) were abnormal in 26 patients (72.2%). Brain-stem trigeminal evoked potentials (BTEPs) yielded similar results, showing distorted waveforms and/or prolonged latencies in 25 patients (69.4%). As expected, the MRI proved to be the most efficient single test, revealing plaques in 86.4% of the patients evaluated. However, the diagnostic accuracy of MRI was lower than that provided by the combination of the BTEP and the BAEP (88.9%). Moreover, in patients having signs of brain-stem involvement, the BTEP, alone and in combination with the BAEP, proved to be more sensitive than the MRI in revealing brain-stem lesions. Correlation between clinical and BTEP findingscould be found only in those patients who presented with signs of trigeminal involvement such as trigeminal neuralgia or dysesthesiae. The analysis of the BTEP waveforms showed two distinct types of abnormality - a peripheral type and a central type - suggesting plaques in distinct locations. Both the BTEP and the BAEP demonstrated a correlation with the clinical course of the disease and the condition of the patient at the time of the evaluation. Relapse of the disease was associatedwith a marked prolongation of the central conduction time in the BTEPand in the BAEP, suggesting the application of such studies to the monitoring of unstable patients or the evaluation of new therapeutic protocols.

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Documento generato il 22/01/20 alle ore 18:28:04